Protein Info for Rv0235c in Mycobacterium tuberculosis H37Rv

Annotation: Probable conserved transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 482 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 94 to 94 (1 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 119 to 140 (22 residues), see Phobius details amino acids 145 to 168 (24 residues), see Phobius details amino acids 229 to 248 (20 residues), see Phobius details amino acids 254 to 278 (25 residues), see Phobius details amino acids 290 to 310 (21 residues), see Phobius details amino acids 388 to 409 (22 residues), see Phobius details PF06762: LMF1" amino acids 121 to 275 (155 residues), 220.7 bits, see alignment E=2.4e-69 amino acids 294 to 469 (176 residues), 217.7 bits, see alignment E=1.8e-68

Best Hits

KEGG orthology group: None (inferred from 100% identity to mbt:JTY_0241)

Predicted SEED Role

"Integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (482 amino acids)

>Rv0235c Probable conserved transmembrane protein (Mycobacterium tuberculosis H37Rv)
MGWFSAPEYWLGRLALERGTAIIYLIAFVAAAQQFRPLIGEHGMLPVPRYLAGQSFWRTP
SIFHFRYSDRVFAGVCWLGAVLSAAVVAGAASFVPLWATMLIWLTLWVLYLSIVNVGQAW
YSFGWESLLLETGFLMIFLGNERTAPPILTLLLARWLLFRVEFGAGLIKMRGDSCWRSLT
CLYYHHETQPMPGPLSWFFHHLPKPLHRIEVAGNHFAQLVVPFGLFTPQPAASIAAAIIV
VTQLWLVASGNFSWLNWLTILLACSAIDTSSAAALLPMPAQPALSAPPQWFAGLVVVFTA
AVLLLSYWPARNLLSSHQRMNMSFNPFHLVNTYGAFGSICRTRREVVIEGTDESPITEQT
VWKAYEFKGKPGDPRRLPRQWAPYHLRLDWLMWFAAISPGYALPWMTPFLNRLLRNDPAT
LKLLRHNPFPQSPPRYVRAQLYQYRFTTVAELRRDRAWWHRTLIGRYVPPMSLRKVASPP
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