Protein Info for Rv0151c in Mycobacterium tuberculosis H37Rv

Annotation: PE family protein PE1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 588 transmembrane" amino acids 512 to 542 (31 residues), see Phobius details amino acids 552 to 577 (26 residues), see Phobius details PF00934: PE" amino acids 42 to 132 (91 residues), 104.1 bits, see alignment E=3.9e-34 PF08237: PE-PPE" amino acids 196 to 415 (220 residues), 245.8 bits, see alignment E=4.2e-77

Best Hits

KEGG orthology group: None (inferred from 100% identity to mbb:BCG_0187c)

Predicted SEED Role

"PE family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (588 amino acids)

>Rv0151c PE family protein PE1 (Mycobacterium tuberculosis H37Rv)
MAPFGFTPKARHNRGVALRSTYRLDGWVMGPVDKEGWGLSYVFAQPSVLAAAATDLAGIG
SAINQATAAVAAPTTGLAAAAADEVSTALATLFGAYGQQFQAISAQVAAFHNEFTQRLAA
AANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQNTAIIMGGTGSPIPTPSYVNA
ITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTSVQLGLQILDGAIWEQINAGNHV
TVFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFILIGNEMNPNGGILARIPGLNVTTLG
LPFYGATPDNPYPTTTYTLEYDGFADFPRYPLNVLSDINAVFGILTVHTTYADLTPAQIA
SATQLPTQGTTSNTYYIIETEHLPLLAPLRAIPVIGPPLAALVEPNLEVIVNLGYGDPRF
GYSTSPANVPTPFGLFPDVPASVVADALVAGTQQGVNDFMVELPAALNTLPQTPMPAFPP
YVPTLLPPPPPPQPATLINIADTFASVVSTGYSILLPTADLGLAFVTILPAYDLTLFVNQ
LAAGNLRAAIELPLAATIGLAALGGMIEFIAIVVTLADITQQLQSFSI