Protein Info for RS_RS24135 in Ralstonia solanacearum GMI1000

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 503 signal peptide" amino acids 1 to 41 (41 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 31 to 480 (450 residues), 514.7 bits, see alignment E=1.1e-158 PF02321: OEP" amino acids 82 to 240 (159 residues), 58.7 bits, see alignment E=3.5e-20 amino acids 304 to 478 (175 residues), 83.7 bits, see alignment E=7.3e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RS05806)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein CmeC" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XQ30 at UniProt or InterPro

Protein Sequence (503 amino acids)

>RS_RS24135 membrane protein (Ralstonia solanacearum GMI1000)
MASIGPRWAWEHALDGWKRCRRLRTRLAALAGGLALSACALQPPYQAPQTAIATQWQAER
PHGASVTSLVDWWSRFNDPAVAELIRRAEADSPSLAKAVAQINSARATLVSNGADAWPAL
TGSASVTRAKSATAAGDTTVSSLSTTRSGGLDASWEIDLFGKVRASRQSAQAQLEARIDD
WHDARVSLAAEVADDYVQYRACRQLAKAYAQAAASRAQTAKSTRAAVAAGMTAASDGYLA
EGSTASANATATEQSVACETLVKSLVALTGTDEPTLRGIIDRPGAPDLPQPDTFSVTSVP
ADLVRQRPDLASAERDLAADYASIAKARANRFPSLSLSGSIAISATTLAAPMSSWSFGPS
LSVPLFDAGQRKAAVDSAQATYDAQLATYRSSVRTAVKEVEQALVALDGAARRSDDARQA
AEQYRRYVSAIETNWRAGLDTLLTLEEARRSATTAEITLIELQRDRVRDWITLYKALGGG
WQADQALASTPHATAAPAQGTTP