Protein Info for RS_RS22615 in Ralstonia solanacearum GMI1000

Annotation: type VI secretion system tip protein VgrG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 760 TIGR03361: type VI secretion system Vgr family protein" amino acids 94 to 611 (518 residues), 510.4 bits, see alignment E=5.2e-157 TIGR01646: Rhs element Vgr protein" amino acids 107 to 597 (491 residues), 384.2 bits, see alignment E=1.1e-118 PF05954: Phage_GPD" amino acids 114 to 429 (316 residues), 304 bits, see alignment E=1.7e-94 PF04717: Phage_base_V" amino acids 485 to 548 (64 residues), 45.7 bits, see alignment E=1e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RS05480)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XQT0 at UniProt or InterPro

Protein Sequence (760 amino acids)

>RS_RS22615 type VI secretion system tip protein VgrG (Ralstonia solanacearum GMI1000)
MSFTSTGNGATPSGNRFFSSLPAGGNALDMGTLASAAAMLGNVPGAGLIGGAARAAELAQ
TGMSLLGRTPASIADALNSAAGARSRLTQDSRFIRMESPLGRDVLLVNAMVVDEYVNRLP
EIHLDLLSHQGDIQIDQIVGQPVSIRLEPKASGSALSQLMAGPDIGKRTFHGYAASFGRV
GHPGAVTRYEMTVVPWFWFLTRSTDCRIFQNRTAEQILSEIFVELGFHDFEFHLKTPPAT
LEYVVMYRESYYNFCARLMEQEGMLWTFRYEADKHVLVIGDTNDTFRPLAPVDSIPYYGS
SAASERNGIDRWDEAFSFRVGKITYRDFNYSTPSSPLMHVEVPTTLKNPNIGSTERYEYH
SMYDLADDGRRYARYAMEAEEAQAHRFEGAGFVQAMTTAGRFRLTHHPMAAYDDKQFVIL
HVRHHAVNDYTGQAAELPYRNAFTCLPLDVPFRPERRTPKPFMYGTQAALVVGPKGEEIY
TDGSRVKVHFFWDRRGKLDGSDSIWVRVSQPWAGAGWGGAAIPRIGQEVIVAFNEGDPDN
PVIVGRVFNGEAANPYHGDNGQTMGIRSQTHKGGGSNELRFSDVNGAQEVYLHAQKDMNT
VVQDAQSTQVLKGDRTILVSTGNHATEVSTGNMSEAIQGDRTTLVAKGNHETTVSTGDMS
ETVSLGDRTITVAKGNQATTVSVGNLTTTVTQGDTTQKTPAGVHTIEAKELWIRVGGSGG
TSIHMTADAIELHKGSSTIRLDGGEIKIQAPNTHINPDNG