Protein Info for RS_RS22535 in Ralstonia solanacearum GMI1000

Annotation: hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 PF13483: Lactamase_B_3" amino acids 83 to 289 (207 residues), 45.5 bits, see alignment E=8.5e-16 PF12706: Lactamase_B_2" amino acids 98 to 290 (193 residues), 163.5 bits, see alignment E=5.1e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RS05497)

Predicted SEED Role

"Outer membrane protein romA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XQU6 at UniProt or InterPro

Protein Sequence (362 amino acids)

>RS_RS22535 hydrolase (Ralstonia solanacearum GMI1000)
MPLCNAASPLPFAASETPAAPGLDGKFRNAVSKPRQGFWQGLGLMWTFFFKRPADTVPDR
ALPTQPLTRDQLLQAPDRTLFRLGHSTVLLKLRGRFWLTDPVFSERASPVQWIGPKRFHA
PPIALADLPDIEGVILSHDHYDHLDRDTVRALAPRVKHFLTPLGVGDRLIDWGVAADKVR
QLNWWQTTTVGGLQFTATPAQHFSGRTLSDGNRTLWASWVLIDDDLRLFFSGDTGYFPGF
KAIGDRFGPFDLTLMETGAYDPRWSYVHMLPEQTLQAHLDLRGRRLVPIHNGTFDLALHP
WQEPFERILSAARAHDVEVVTPMIGAALDIVRPAATPAWWRPQPETPRGAVTPSLAAGHA
GD