Protein Info for RS_RS20650 in Ralstonia solanacearum GMI1000

Annotation: type VI secretion system protein ImpK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 211 to 230 (20 residues), see Phobius details TIGR03349: type IV/VI secretion system protein, DotU family" amino acids 33 to 238 (206 residues), 194.3 bits, see alignment E=1.1e-61 PF09850: DotU" amino acids 34 to 231 (198 residues), 200.6 bits, see alignment E=1.1e-63

Best Hits

KEGG orthology group: K11892, type VI secretion system protein ImpK (inferred from 100% identity to rso:RS01969)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XRU2 at UniProt or InterPro

Protein Sequence (263 amino acids)

>RS_RS20650 type VI secretion system protein ImpK (Ralstonia solanacearum GMI1000)
MSATTTPSLFGGSAAPAGNAAADARESNTHVRTLLDLLYDGFFMLFQLRNGQQPTSAEDF
LTRVRAFLEDFDRGAKRLNVSAEDVFDAKYAFCAAVDETILSSNFSIRTAWERRPLQLEL
FGEQLAGETFFIKLEELRAHGAPRLQALEVFHMCLLLGFRGKYILEGPEKLAYLTARLGD
EISAIKGKRAAFAPHWLLPDKVSHRLKRETPLWIFGAVFALIALLGYIGLSSTLRAKTNE
TLEGYSQVIKLGPRFSHLTISLP