Protein Info for RS_RS20315 in Ralstonia solanacearum GMI1000

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 60 to 84 (25 residues), see Phobius details amino acids 92 to 110 (19 residues), see Phobius details amino acids 113 to 138 (26 residues), see Phobius details amino acids 150 to 172 (23 residues), see Phobius details amino acids 180 to 198 (19 residues), see Phobius details amino acids 224 to 247 (24 residues), see Phobius details amino acids 258 to 279 (22 residues), see Phobius details amino acids 290 to 308 (19 residues), see Phobius details amino acids 314 to 336 (23 residues), see Phobius details amino acids 343 to 366 (24 residues), see Phobius details amino acids 376 to 397 (22 residues), see Phobius details PF07690: MFS_1" amino acids 42 to 355 (314 residues), 80.7 bits, see alignment E=5.2e-27

Best Hits

Swiss-Prot: 37% identical to YYCB_BACSU: Uncharacterized transporter YycB (yycB) from Bacillus subtilis (strain 168)

KEGG orthology group: K03449, MFS transporter, CP family, cyanate transporter (inferred from 100% identity to rso:RS01782)

MetaCyc: 38% identical to 2-nitroimidazole exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-273; TRANS-RXN0-596

Predicted SEED Role

"MFS transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XS14 at UniProt or InterPro

Protein Sequence (407 amino acids)

>RS_RS20315 MFS transporter (Ralstonia solanacearum GMI1000)
MHRPPQPAANPLHDTAGRRSAGALAMLVAGLVLVGVNLRPALSSLSPVLKQVAAGTGLSG
ATAGLLTTLPVVCLGVFAPAAAVLARRFGAERTVGGLLIVLALGIALRSAGGIVALFAGT
LAAGACIGVTGILLPGIIKRDFGRQADLMTGVYTMALCLGAAVAAGASAPLAALLGGWQP
ALAFWALPALLAFAGWWPHMRHPHAGGAAARIERVALWRQPIAWQVMLYMGLQSSLAYCV
FGWMPVILQDRGLSAVQSGMVVAVSVLVQLITALGGPFIARLSRDQRPTVLLMMLMTWAG
LMGCLYAPVSTLWWWAVLMGLGQGGNFSVALSLIVLRSADARVAASLSAMTQGGGYTLAA
AGPYLMGVLHDLTGGWAAMGWLFSAIALSALVLGMLAGRNRTLHAGA