Protein Info for RS_RS19650 in Ralstonia solanacearum GMI1000

Annotation: type VI secretion system tip protein VgrG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 908 TIGR03361: type VI secretion system Vgr family protein" amino acids 32 to 570 (539 residues), 241 bits, see alignment E=2.3e-75 PF05954: Phage_GPD" amino acids 45 to 371 (327 residues), 239.7 bits, see alignment E=9.1e-75 TIGR01646: Rhs element Vgr protein" amino acids 45 to 579 (535 residues), 192.2 bits, see alignment E=1.7e-60 PF04717: Phage_base_V" amino acids 475 to 523 (49 residues), 26.4 bits, see alignment 1.5e-09 PF13296: T6SS_Vgr" amino acids 552 to 658 (107 residues), 104 bits, see alignment E=9.6e-34 PF10106: DUF2345" amino acids 690 to 834 (145 residues), 115.6 bits, see alignment E=3.6e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RS00397)

Predicted SEED Role

"PUTATIVE VGR-RELATED PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XSF8 at UniProt or InterPro

Protein Sequence (908 amino acids)

>RS_RS19650 type VI secretion system tip protein VgrG (Ralstonia solanacearum GMI1000)
MNADVTSIQLPCALAQNRRAMRLDFGPAATAAAQTLVPQYADIHQGICAGLEAQVVCLSE
RADLSRDELLGLPVSIQVATDGGALHAINGIVSDVHSGAFDGTLASYRLTIIDAMSLMRR
RRNMRIFVGKSVPDILGILLAEWQQRSAILGQAFRFQLLLDRSGYPVRAQTLQLDESDSG
FLDRLTRREGMFCFVVAGTPDGSDGDTPAQTLVFCDDPMKLPQAQAGAVPFHYGAAVKAR
DSVTRWGEAHSLVSGTIRGTSPDYETGRVDRVDVDTLLDLGKAGNDLARLMTDAAVDRAH
AGDSRADYERQGRLRMQAHERRAAYVHAASDVRNLTPGSWFVLSGHPLVDKREPEQREFV
VTRLRQRIANNFPKALNEQARALAEASGWHLEVRPGRDDAQIRYENTFTCVPRGAPLTPD
YDPRIDLPRTDPMTAVVVGPNGQEVHCDELGRYKLQFVGLYAEDHAHAQGAGTSGTERDS
AWVRAGNLWAGQRYGINLPLRAGMEVLVAFANGDPDRPYIATVLPGHNNMPTAFNDTGAL
PDNKHLSGIKTKEVDGSGFNQVAFDDTPGEISSQLASTHAASQLSLGYLTHPRDQGKAEP
RGEGAAITTQAMASMHGNQGMLLSTERRSQAGNQMDRDGLLGLAQAFASVAAEFGKMAAT
HHAGTYDPAPLKQLIRQLQDWEHGTNTAPQGAGQGGTPLIALSSPAGIVAGSADNIALAA
QTSVDVMSGDNTQISAGKDALIYATNEVSIFAVEGGVRVVTAKGDVVVESHTGNIALNGA
KRITLNAGEEIVLNAPRVRTVTQGAQTTWGGGEIVEEASGGYTIKSANFQQIGGGGAPAA
SNLPANDRHFDRHLRLTDQLTGEPIANRRYRATLADGQVVEGVSDAQGYAKHLKSSITFA
HYSLEILD