Protein Info for RS_RS18855 in Ralstonia solanacearum GMI1000

Annotation: NAD(P)/FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 PF01494: FAD_binding_3" amino acids 14 to 263 (250 residues), 77.3 bits, see alignment E=6.1e-25 PF00890: FAD_binding_2" amino acids 15 to 46 (32 residues), 22.1 bits, see alignment (E = 3.7e-08) PF04820: Trp_halogenase" amino acids 15 to 88 (74 residues), 33.7 bits, see alignment E=8.6e-12 amino acids 106 to 364 (259 residues), 54.5 bits, see alignment E=4.2e-18 PF03486: HI0933_like" amino acids 15 to 45 (31 residues), 23.2 bits, see alignment (E = 1.3e-08) PF12831: FAD_oxidored" amino acids 15 to 176 (162 residues), 41.1 bits, see alignment E=6.8e-14 PF13450: NAD_binding_8" amino acids 18 to 47 (30 residues), 29.4 bits, see alignment (E = 3.7e-10)

Best Hits

KEGG orthology group: K00540, [EC: 1.-.-.-] (inferred from 100% identity to rso:RS00759)

Predicted SEED Role

"FIG022199: FAD-binding protein"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.-.-.-

Use Curated BLAST to search for 1.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XSW3 at UniProt or InterPro

Protein Sequence (419 amino acids)

>RS_RS18855 NAD(P)/FAD-dependent oxidoreductase (Ralstonia solanacearum GMI1000)
MIKKQDPLNHPESVDVAIIGAGPAGAVAAALLRQAGQQVLVLERQHFPRFSIGESLLPQS
MAYLEQAGMLRAVVEAGFQYKNGAYFVHGDKTAAFDFRDKHSDGWGTTYQVERAAFDQIL
INCAADQGADVRFGHSVRAVQPGDAPVLEVQTESGDTYTVHARFILDASGFGRVLPRLLN
LEAPTGMPLRAALFSHVQDALPAGMTDRNKICIAVHPERRDVWYWMIPLANGRSSVGCVA
EASFLDIPEAEREAALRALIRAEPNIASLIGDAPFLMPVRHIGGYAANVEKLHGPGYALL
GNAGEFLDPVFSSGVTIALRSADLAVRALLRQLAGETVDWQSVYDVPLRRGIDTFRAFIE
RWYTGELQDIIFHPQQAPGIRRMISAILAGYAWDETNPFVADPVRRLNTLHEVCRLEAV