Protein Info for RS_RS16295 in Ralstonia solanacearum GMI1000

Annotation: thiosulfohydrolase SoxB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR04486: thiosulfohydrolase SoxB" amino acids 2 to 560 (559 residues), 851 bits, see alignment E=1.7e-260 PF02872: 5_nucleotid_C" amino acids 392 to 519 (128 residues), 55.1 bits, see alignment E=9.2e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RSc3253)

MetaCyc: 51% identical to SoxB (Paracoccus pantotrophus)
RXN-11952 [EC: 3.1.6.20]; 3.1.6.20 [EC: 3.1.6.20]; SOXA-FDENIT-RXN [EC: 3.1.6.20]

Predicted SEED Role

"Sulfur oxidation protein SoxB" in subsystem Sulfur oxidation

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.6.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XUD8 at UniProt or InterPro

Protein Sequence (572 amino acids)

>RS_RS16295 thiosulfohydrolase SoxB (Ralstonia solanacearum GMI1000)
MNRREFVQALAVAAAAGLHLTDARAADTSLYDLPRFGNVHLLHFTDCHAQLLPIEYREPS
VNLGVAQWAGQPPHLVGRALLERYGIAPGSRAAHAFTALDFTEAARRFGRMGGFAHLATL
VKRLRATRPDALLLDGGDTWQGSATSLWTRGQDMIDAALLLGVDVMTPHWELTYGAERVR
HVVDHDFRNKVAFVAQNIQTTDFGDPVFDPYVLRELNGVPVAIIGQAFPYTPIAHPADFT
PDWTFGIQEARLQERVDEARGKGARVVVLLSHNGMDVDLKLASRVRGIDAILGGHTHDAV
PAPVRVSNPGGTTLVTNAGSNGKFVGVLDLDVRGGTVRDLRYTLLPVFADLLPPDPAMAA
LIERVRAPYRDKLGEVLAVNRDLLYRRGNFNGTFDQLIVDGLMQAQGAEIAFSPGFRWGT
TLLPGEPLTLEALMAQTAITYPATTLTDMTGATIKTILEDVADNLFNPDPYYQQGGDMVR
TGGLRYAIDPTQPIGRRITDLRLDDQPLDADRRYKVAGWAAVSAEARRTAGRPVWDVLAD
WLRDQHEVTARPLNTPRIVGVAGNPGIDTERG