Protein Info for RS_RS13875 in Ralstonia solanacearum GMI1000

Annotation: magnesium and cobalt transport protein CorA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 transmembrane" amino acids 261 to 282 (22 residues), see Phobius details amino acids 294 to 313 (20 residues), see Phobius details TIGR00383: magnesium and cobalt transport protein CorA" amino acids 2 to 319 (318 residues), 253.6 bits, see alignment E=1.5e-79 PF01544: CorA" amino acids 28 to 315 (288 residues), 198.6 bits, see alignment E=7.5e-63

Best Hits

Swiss-Prot: 44% identical to CORA_SALCH: Magnesium transport protein CorA (corA) from Salmonella choleraesuis (strain SC-B67)

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 100% identity to rso:RSc2774)

MetaCyc: 44% identical to Ni2+/Co2+/Mg2+ transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-141; TRANS-RXN-141A; TRANS-RXN-141B

Predicted SEED Role

"Magnesium and cobalt transport protein CorA" in subsystem Campylobacter Iron Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XVQ6 at UniProt or InterPro

Protein Sequence (320 amino acids)

>RS_RS13875 magnesium and cobalt transport protein CorA (Ralstonia solanacearum GMI1000)
MINLFVVQKGRLAQEQVEDRNELLQHKPIWIDVIDPDDEELAWIKDTYGVVLPELEQLGD
LEASARYFEGEDSHIHIRTDFLLDEETSSRNVRVAFVLTKDVLFSIHDEDLPAFRLVRMR
ARLRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEDASKRVLADEVTDQAAADVLEI
IARVEDLNGRIRRNVMDTRRAVSFLLRSQMLSPDQQDEARQVLRDIDSIENHTAFLSDKV
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKVMPELDWAEGYPYAIV
LMIVSAAIPLVYFRRKGWLK