Protein Info for RS_RS13750 in Ralstonia solanacearum GMI1000

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 347 PF00126: HTH_1" amino acids 7 to 64 (58 residues), 48.7 bits, see alignment E=5.8e-17 PF03466: LysR_substrate" amino acids 94 to 304 (211 residues), 73.2 bits, see alignment E=2.1e-24

Best Hits

Swiss-Prot: 100% identical to PHCA_RALSO: HTH-type transcriptional regulator PhcA (phcA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: None (inferred from 100% identity to rso:RSc2748)

Predicted SEED Role

"small molecule metabolism; global functions; global regulatory functions"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P52698 at UniProt or InterPro

Protein Sequence (347 amino acids)

>RS_RS13750 transcriptional regulator (Ralstonia solanacearum GMI1000)
MVNVDTKLLVIFVELLSKRNATYVAEKMHMTAPAVSHSLGRLREIFDDPLFIRVPHGLTP
TPKALELGPKVREMLDLWAAINEGDIATFDPLEAAGTFNISFAGTLGDALFDRFLLRVKR
LAPGLQVRLTESSSWEADVAAMRSNELDLAFSPFPTRHPEIVEEVVTSFNMWVCARKDHP
VLKDHCSLDQYLECEHIFIAQGNPGTRAAPSLIPLDYALQQRGLKRHSTMTVHAWRTQAE
VAAQTDMIFTVNSLMKDLVCETYNLNAFPLPSELETVLGLNMLWHRSRNTHPMLVWARNL
FKQVVAEYTGKASIAPMHPPMLTDDSGKSGKTGKGDAEKEDESRLSV