Protein Info for RS_RS13290 in Ralstonia solanacearum GMI1000

Annotation: MprA protease, GlyGly-CTERM protein-sorting domain-containing form

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 655 to 673 (19 residues), see Phobius details PF00082: Peptidase_S8" amino acids 184 to 492 (309 residues), 148.8 bits, see alignment E=1.1e-47 TIGR03867: MprA protease C-terminal rhombosortase-interaction domain" amino acids 652 to 678 (27 residues), 37.3 bits, see alignment (E = 1.5e-13)

Best Hits

KEGG orthology group: K14645, serine protease [EC: 3.4.21.-] (inferred from 100% identity to rso:RSc2654)

Predicted SEED Role

"Extracellular protease precursor (EC 3.4.21.-)" (EC 3.4.21.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XW21 at UniProt or InterPro

Protein Sequence (679 amino acids)

>RS_RS13290 MprA protease, GlyGly-CTERM protein-sorting domain-containing form (Ralstonia solanacearum GMI1000)
MKTLVPGGIVRALVALGLVSYQAVPALATGKTGMTDTRLQWVTQLIVKEKSATGSTARTQ
SVAADVATVQRWSVAAQLPVTYKRAMSGGAHVVTLSKGMSAADAQTIAARMESSGQFEYV
SPDTILRPAATPTDPWFANQWNLLPATGTVSTVTTRSGATAANGATTKGGANLTTAWDTT
KGSNTVTVTVIDTGLLAGHADLSGATIQPGYDFVSSTAMTGTPDPVTNLSIPSGFVENDA
TAGRDSDPTDPGDWITTSDATNYPSFCGTSVTDSSWHGTFVTGLIAAQHNAIGVAGVAPG
VSVQMTRAIGKCGGASSDILDALTWAAGGTVPGVTTNATPAKVINMSLGGSTACTTAQQS
AITAARSLGATIVVATGNEFQNAAIDAPASCSGTIAVTAHTLEGDIANYANVGTGTTLSA
PGGGNGSTATGLGALVPSTSNAGTTTASTDTYVGEEGTSMSTPQVAGVAALMLSVNAALT
PDQIKTILQTSSRPFPPDTFCTTHAGVCGAGMLDAGSAIAQAQGVPTVHASVSSSSVTTG
TQVTLQAVGGAGFGKTVGSLSWAQTAGSAVTLSAGSLDSTGNATATFTPTDAGTYTFTVT
LVSSDGTTVSDTTSLTVTAASTSGGTGGSTGGSTGTLPFSGGTSGIGPLNNGGGGLLPLW
LGGLLLAAGALGFQRRKRA