Protein Info for RS_RS12040 in Ralstonia solanacearum GMI1000

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00005: ABC_tran" amino acids 38 to 186 (149 residues), 95.2 bits, see alignment E=5.7e-31

Best Hits

Swiss-Prot: 40% identical to YUSV_BACSU: Probable siderophore transport system ATP-binding protein YusV (yusV) from Bacillus subtilis (strain 168)

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 100% identity to rso:RSc2398)

MetaCyc: 38% identical to iron(III) hydroxamate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-11-RXN [EC: 7.2.2.16]; TRANS-RXN-297 [EC: 7.2.2.16]; TRANS-RXN-298 [EC: 7.2.2.16]

Predicted SEED Role

"Iron(III) dicitrate transport ATP-binding protein fecE"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.34 or 7.2.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XWS2 at UniProt or InterPro

Protein Sequence (279 amino acids)

>RS_RS12040 ABC transporter ATP-binding protein (Ralstonia solanacearum GMI1000)
MSWLRRAAVTDAFAQAADAPALALRELRVTMGGRVLIERLSMSAAGGELWCVVGPNGAGK
STLLGVLAGLRAPDGGAVALDGRALAAWPVAALARRRAFLPQTLHDPFPMTAHEAVMTGR
HPHLARWEWEGEADARAVDAAIAALALEPLAPRDVRTLSGGERQRVAMAAVVAQQASVLL
LDEPLAHLDLHQQIAVLRLLRDGCRRQGWLVILTVHDLNLARRYATHALLMDGEGHAAAG
PADAVLTPEHCARVLRTPIAAVDDGRRIALIPDDPDDAS