Protein Info for RS_RS11930 in Ralstonia solanacearum GMI1000

Annotation: 4Fe-4S dicluster domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 719 PF00037: Fer4" amino acids 206 to 227 (22 residues), 28.2 bits, see alignment (E = 6.2e-10) amino acids 360 to 382 (23 residues), 31.4 bits, see alignment (E = 6.1e-11) amino acids 584 to 606 (23 residues), 26.9 bits, see alignment (E = 1.6e-09) PF12800: Fer4_4" amino acids 209 to 223 (15 residues), 19.7 bits, see alignment (E = 4e-07) amino acids 363 to 379 (17 residues), 18.3 bits, see alignment (E = 1.2e-06) amino acids 589 to 602 (14 residues), 15.8 bits, see alignment (E = 7.5e-06) PF12838: Fer4_7" amino acids 334 to 380 (47 residues), 38.7 bits, see alignment 5.7e-13 amino acids 590 to 636 (47 residues), 32.5 bits, see alignment 4.8e-11 PF13187: Fer4_9" amino acids 335 to 380 (46 residues), 30.7 bits, see alignment 1.3e-10 amino acids 590 to 637 (48 residues), 30.8 bits, see alignment 1.2e-10 PF12837: Fer4_6" amino acids 359 to 381 (23 residues), 30.1 bits, see alignment (E = 1.7e-10) amino acids 584 to 606 (23 residues), 27.9 bits, see alignment (E = 8.2e-10)

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RSc2376)

Predicted SEED Role

"Iron-sulfur cluster-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XWU4 at UniProt or InterPro

Protein Sequence (719 amino acids)

>RS_RS11930 4Fe-4S dicluster domain-containing protein (Ralstonia solanacearum GMI1000)
MPTLVCSCNHTMPLDADAVSDGLRASGAPIDAPGQTHHLLCRREIGAFSRALDGDEDVIV
ACTQEAALFTEVAARHGGVTAPIHFVNVRETGGWSAGARRDARGFHAKAAALLAVAGLPA
PDPVPVVDYRSDGSLLIVGPAERALPWAERLADQLSVTVLATGRDRGAGPLSPPMARRWP
IQAGERVQVSGWLGAFDVQWQSRNPIDLDRCTRCNACIDACPEDAIDTLYQIDLEACRDH
RDCVRACGEAMAIDFGRLDAPQTASGRFDLILDLNDAPAFAQHQPPQGYFHAGADAGRQL
TASLALLQLVGEFEKPRFFQYKASICAHGRNGQVGCDACVRVCSAAAITSQWKDGRGSVH
VTPNLCVGCGACTTACPTGALTYAYPSAPYQGRKLKTLLSTHAAAGGHDAVVLLHNGGRG
RALIEQLGRAARTGKAQGVPVNVLPVEVFHAASTGLDLWLSALAYGAARIAILLTEDDAP
QYRAMLAEQAAVARAVLAGLGEPADAAGVVLIDAPDAGALDARLNAVEVCGPVQGFRADM
PPATFAVAAAKRETLAFALDHLARHAGAVDAVIPLPAGAPFGAIEVDRARCTLCMACVSA
CPSQALRDAAERPVLSMIERNCVQCGLCDTTCPEDAIALVPRLNLSADARQPVVLNETQP
FHCIRCGKPFGTAQMVAAMMARLGAHPAFAGAAGERLKMCGDCRVIDMLEGGEQPGATH