Protein Info for RS_RS10195 in Ralstonia solanacearum GMI1000
Annotation: urease subunit alpha
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to URE1_RALSO: Urease subunit alpha (ureC) from Ralstonia solanacearum (strain GMI1000)
KEGG orthology group: K01428, urease subunit alpha [EC: 3.5.1.5] (inferred from 100% identity to rso:RSc2032)MetaCyc: 74% identical to urease alpha subunit (Sinorhizobium meliloti Rm2011)
Urease. [EC: 3.5.1.5]
Predicted SEED Role
"Urease alpha subunit (EC 3.5.1.5)" in subsystem Urea decomposition (EC 3.5.1.5)
MetaCyc Pathways
- urea degradation II (1/1 steps found)
- superpathway of allantoin degradation in plants (4/8 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- Atrazine degradation
- Purine metabolism
- Urea cycle and metabolism of amino groups
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.5
Use Curated BLAST to search for 3.5.1.5
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q8XXT1 at UniProt or InterPro
Protein Sequence (572 amino acids)
>RS_RS10195 urease subunit alpha (Ralstonia solanacearum GMI1000) MTLKITRRAYAEMFGPTTGDRVRLADTDLIVEVERDYTIYGEEVKFGGGKVIRDGMGQSQ RESKDCADTVITNALIIDHWGIVKADIGLKHGRIAAIGKAGNPDIQPGVTIVIGPGTEII AGEGMIVTAGGVDTHIHFICPQQIDEALNSGVTTMIGGGTGPATGTYATTCTPGPWHLQR MLQAADAYPMNIGFLGKGNGSLPGALREQIDAGAIGLKLHEDWGSTPAAIDCCLGVADDT DTQVAIHTDTLNESGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIRVCGESNVLPSSTN PTRPFTVNTLDEHLDMLMVCHHLDASIAEDIAFAESRIRRETIAAEDILHDLGAFSMLSS DSQAMGRVGEVILRTWQTAHKMKAQRGKLAGDPNDARGGHDNFRVKRYVAKYTINPAITH GIAHEVGSIEVGKWADLVLWKPAFFGVKPSLILKGGMIASAAMGDANASIPTPQPVHYRP MFAAAGGALARSSLSFLSQSAAQAGVAERYGLAKTTAVVRGTRAVTKAQMIHNDWQPSIT VDPETYQVVADGMLLTCEPAEVLPMAQRYFLF