Protein Info for RS_RS09220 in Ralstonia solanacearum GMI1000

Annotation: indolepyruvate oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 503 transmembrane" amino acids 379 to 396 (18 residues), see Phobius details PF01558: POR" amino acids 14 to 204 (191 residues), 37.1 bits, see alignment E=3.8e-13 PF20169: DUF6537" amino acids 250 to 459 (210 residues), 156.9 bits, see alignment E=7e-50

Best Hits

KEGG orthology group: K00180, indolepyruvate ferredoxin oxidoreductase, beta subunit [EC: 1.2.7.8] (inferred from 100% identity to rso:RSc1828)

Predicted SEED Role

"Indolepyruvate oxidoreductase subunit IorB II (EC 1.2.7.8)" in subsystem Aromatic amino acid interconversions with aryl acids (EC 1.2.7.8)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.8

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XYD0 at UniProt or InterPro

Protein Sequence (503 amino acids)

>RS_RS09220 indolepyruvate oxidoreductase (Ralstonia solanacearum GMI1000)
MTVEPIKIAILAMGGEGGGVLADWIVDLGEANGYFAQTTSVPGVAQRTGATIYYVELFPG
AADAPARAPVLALMPMPGDVDVVLASELMEAGRAVQRGFVTRERTTLIASSHRVYSIAEK
SAMGDGRVDSDGLARQAREAARHFFSFDMAEAAERAGSVVSAVLFGALSGSGVLPFSREQ
FEATIERGGVGVKPSLKAFDAGYARARPGQPDGTADAPRPMPADAAPAPRDPAVAVLLER
ARRFAPQVSAIAIEGVRRLIDYQDPAYAGLYLDRLDALSAAPGGSQPDLLGETARHLALW
MSYEDTIRVADLKTRGSRFERVRGEVRAKSDQLLQINEFMHPRIEEICETLPAGLGRWLA
RPHWAHRLVARFTRQGRVVKTSSLGGFLLLYTLARWGRWRRTTLRYALENARIEAWLRRV
RAVAAINPALALETAQCQRLVKGYGDTHARGLKHYETLMTVVDRHADTLPPQTLRELRDA
ALADEHGNQLRACLQRHAFSVEG