Protein Info for RS_RS08170 in Ralstonia solanacearum GMI1000

Annotation: potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 52 to 77 (26 residues), see Phobius details amino acids 110 to 133 (24 residues), see Phobius details amino acids 147 to 167 (21 residues), see Phobius details amino acids 178 to 199 (22 residues), see Phobius details amino acids 221 to 243 (23 residues), see Phobius details amino acids 255 to 277 (23 residues), see Phobius details amino acids 297 to 326 (30 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 373 to 395 (23 residues), see Phobius details amino acids 405 to 427 (23 residues), see Phobius details amino acids 433 to 451 (19 residues), see Phobius details PF02705: K_trans" amino acids 22 to 554 (533 residues), 748 bits, see alignment E=2.9e-229

Best Hits

Swiss-Prot: 100% identical to KUP2_RALSO: Probable potassium transport system protein kup 2 (kup2) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 100% identity to rso:RSc1621)

MetaCyc: 49% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XYY5 at UniProt or InterPro

Protein Sequence (633 amino acids)

>RS_RS08170 potassium transporter Kup (Ralstonia solanacearum GMI1000)
MSQALTATGSSQSNVNLRAMVVGAVGVVFGDIGTSPLYALKECFSPEHGIPFSTAAVLGI
ISMLFWAMVIVVSLKYVLFVMRADNNGEGGILALMALSLRTANKQSKRMALLTMLGVFGA
CMFYGDAVITPAISVLSAMEGLEIAAPSLSPFVLPITVVILAALFLIQRGGTSVVGKLFG
PVMLVWFAALAALGLVNLMKAPQILVAVNPVYAIAFLHEHALQAFVVLGSVFLVLTGAEA
LYADMGHFGARPIRWGWFFIVAPSLLLNYFGQGAMLLTDPSTVENPFYRAVPEALQLPMV
VLAAAATVIASQAVISGAFSLTSQAIQLGFVPRMRIRYTSEAEIGQIYVPVVNWMLLILV
ISVVLAFKKSDNLAAAYGIAVTTTMVITTVLAAVVMRSVWRWNPVLVTLVSLGFLVVDMA
FFSANLLKIRDGGWFPLMLGGAVFFLLMTWYKGRQLVRARSLEDGIPLEPFLAGLLAHPP
HRVEGTAVFLTANIDFVPVSLLHNLKHNRVLHERVIFISFVTRDIPYVDDRCRVTVREFG
SGIYLVKAEYGFKETPDVYRVLELGQPQIGSRCELMDTSFFIARESVVPSKLPGMSMWRE
RLFAWMHQNGAKPSDFFHIPANRVVELGTKVEI