Protein Info for RS_RS05745 in Ralstonia solanacearum GMI1000

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 41 to 62 (22 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 95 to 117 (23 residues), see Phobius details amino acids 128 to 149 (22 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 203 to 226 (24 residues), see Phobius details amino acids 233 to 255 (23 residues), see Phobius details amino acids 266 to 285 (20 residues), see Phobius details amino acids 291 to 315 (25 residues), see Phobius details amino acids 331 to 353 (23 residues), see Phobius details amino acids 362 to 382 (21 residues), see Phobius details PF07690: MFS_1" amino acids 8 to 319 (312 residues), 155.4 bits, see alignment E=1.9e-49 PF06779: MFS_4" amino acids 12 to 373 (362 residues), 50.9 bits, see alignment E=1.6e-17

Best Hits

Swiss-Prot: 53% identical to YTBD_BACSU: Uncharacterized MFS-type transporter YtbD (ytbD) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to rso:RSc1153)

Predicted SEED Role

"Major facilitator superfamily MFS_1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y091 at UniProt or InterPro

Protein Sequence (400 amino acids)

>RS_RS05745 MFS transporter (Ralstonia solanacearum GMI1000)
MPIALLALTLSAFAIGTTEFVIVGLIPTVAADLGITLPSAGWLVSLYALGVAVGAPVLTA
LTGRLPRKALLLALMALFTLGNLLAWRAPGYAPLVLARVMTGLAHGVFFSIGSTLATSLV
PREKAASAIAIMFTGLTVALVTGVPLGTFIGQHFGWRETFLAVAGLGVIAFVGSLVFVPR
DIAHAPPASLARQLQVLAQPRLLMVYAKTAIGYGGSFIPFTFLAPILQDVAGFSAGAVGW
VMLVYGVSVAAGNLWGGRLADRKGPIAALQVIFALLAAVLFAFTFTARYPWTAVATVLLW
GAVAFGNVPGLQAYVVKQAERFAPQAVDVASGLNIAAFNLGIAGAAWAGGWIVTHLGLMH
TPWIGALVVLVSLGLTAWSGALDRRGGIGPRLDGPAPVGH