Protein Info for RS_RS05340 in Ralstonia solanacearum GMI1000

Annotation: CHASE2 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 784 transmembrane" amino acids 25 to 48 (24 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 335 to 354 (20 residues), see Phobius details amino acids 359 to 378 (20 residues), see Phobius details PF05226: CHASE2" amino acids 38 to 319 (282 residues), 195.4 bits, see alignment E=2.1e-61 PF08448: PAS_4" amino acids 440 to 555 (116 residues), 52.3 bits, see alignment E=9.2e-18 PF02518: HATPase_c" amino acids 668 to 778 (111 residues), 92.5 bits, see alignment E=3.6e-30

Best Hits

KEGG orthology group: K00936, [EC: 2.7.3.-] (inferred from 100% identity to rso:RSc1075)

Predicted SEED Role

"Signal transduction histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y0G9 at UniProt or InterPro

Protein Sequence (784 amino acids)

>RS_RS05340 CHASE2 domain-containing protein (Ralstonia solanacearum GMI1000)
MTGPATPVPDRQAARAVALRPGLRALLEWVLLVALAVLLTFGAVRWSVVARLDAALYDTV
LSLHGHAPRDDIVIVAIDDQSLEAVGRWPWPRARLAELVARVGAAHPRAVGVDILLIEPD
LTDPEGDRALAAAFAQAGQVILPALPERTGQGRVFHYPFLGIGTHVAHIDAAPDPDSVVR
GLYLAEGPRGHLLDHLALQLARQAGPALAGDVPRRTEIDADGWARRANIGVNFAGPAGTF
RHVPALTLLQGGVPADAFSGKLVLIGATASGVSDIFATPTSRTMSGVEVLANATQTLLDG
NAILPASRTVFWLVTLLPLSLTACALLWLTPRMALTAALGSAGLLLVGVVAALAGWNRWL
PPFAALVGPLVLYPLWSWRQQEAALRFLRDELHRLAREPGLLAGTGPLAQTGRTLDAHMD
AVASLTDKLRGLRRFLAEALESLPDATVICTHDGDIRLANGRSADLAAQAPVSGQDRAAA
LRDLPTLLACAFEDPAPGQHYWTRWLTAPDTAQEPVELRTRDGRSMLMHAAALRDDAGRP
MDIIVSFADITAVRQAERHREEALRFISHDMRSPQSAILALIELQRDAGRALGHEALLAR
IQQLSSRTLELADAFIDLARVESQELKLTDVDLVGLVLDAADEVWALANHHQIEVRVDAD
LEASVRGEPRMLVRALVNLVNNAIKFSPRGTTVTVAVRGDADSFAVSVADQGVGIAAEDQ
AQLFQPFRRLHEAVADAPSGSGLGLVFVKTVVERHGGRIAVRSVPGHGATFTLWLPRASR
PGAF