Protein Info for RS_RS04730 in Ralstonia solanacearum GMI1000

Annotation: ergothioneine biosynthesis protein EgtB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 TIGR03440: ergothioneine biosynthesis protein EgtB" amino acids 30 to 430 (401 residues), 425.1 bits, see alignment E=1.9e-131 PF03781: FGE-sulfatase" amino acids 210 to 352 (143 residues), 103.7 bits, see alignment E=7.1e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RSc0951)

Predicted SEED Role

"Serine/threonine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y0U2 at UniProt or InterPro

Protein Sequence (432 amino acids)

>RS_RS04730 ergothioneine biosynthesis protein EgtB (Ralstonia solanacearum GMI1000)
MAEFFMLPDPTFIGALSDWNDGRRLPRQGIAHSLVDARNRTLALLAAFGDTQRGWQIERV
LHHAPPLWTLGQLAWFAEFWCLREPRRVGEDAVEDGGGTEWALPRWQATLPAGLDGADSF
FDMDRMPPDACWALTLPGIATIKQYAHDVLDRVLRKLATLGTDEDAALEPFRWAVFHEDL
RAEHLHGLLQVLGLQPAGQPPLAAVVVPAARTLSLPGGRFQMGWPDADGFVFDNECPPHR
TYVPAFEIDAQPVTNGQYLEFVEDGGYDHPQWWSAAGMEWLMMQERSAPLGWRRDPASRT
WQVVRYGQPRTLNRDEPARHVSLYEAQAWCRWAGRRLPTEDEWEMAAVLGRAGFHWGQVW
EWTSSPFEPYPDFVPGAPRGRVATLSAPHFMTMQTVRGAAAHTPQRVRHPRFRGFLLPER
DDVFVGFRTCAL