Protein Info for RS_RS04045 in Ralstonia solanacearum GMI1000

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 115 to 137 (23 residues), see Phobius details amino acids 147 to 173 (27 residues), see Phobius details amino acids 179 to 199 (21 residues), see Phobius details amino acids 220 to 246 (27 residues), see Phobius details amino acids 263 to 280 (18 residues), see Phobius details amino acids 291 to 309 (19 residues), see Phobius details amino acids 315 to 333 (19 residues), see Phobius details amino acids 345 to 364 (20 residues), see Phobius details amino acids 379 to 398 (20 residues), see Phobius details PF06779: MFS_4" amino acids 33 to 395 (363 residues), 421.6 bits, see alignment E=3.4e-130 PF07690: MFS_1" amino acids 33 to 337 (305 residues), 36.9 bits, see alignment E=2.1e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to rso:RSc0805)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y185 at UniProt or InterPro

Protein Sequence (406 amino acids)

>RS_RS04045 MFS transporter (Ralstonia solanacearum GMI1000)
MQHTLSSSLSSLPAAHATRTAAWRVAIAGMVALSVAMGIGRFAFTPILPMMLHDGSVTLG
QGSWLATLNYLGYFVGALACMALRGDAARLIRIGLVATVLLTAGMGVLQGQPAWLVLRFA
AGVVSALVFVFTAGWCLHRLTELGHAALGGIIFCGPGLGIAVPGLVASGMVALGWHASSA
WIAFGVLSAVLSAAVWPTVRPERRPHAAASAPGISGAAPGLGLPTVIITLAYGLAGFGYI
VTATFLPVIARRVLPAGSIWPDLFWPIFGVGVALGALLSTRISLARDNRTLLAAAYAMQA
VAVAASIVWPTVGGLALSSLLLGLPFTAITLFAMREARRLWPHAVPRLMGLMTAVYGIGQ
IAGPPLANRLFAATGGFDASLAAAAASLVLGMAMFLAVRRIAPAGA