Protein Info for RS_RS04035 in Ralstonia solanacearum GMI1000

Annotation: serine protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 261 to 283 (23 residues), see Phobius details amino acids 290 to 309 (20 residues), see Phobius details amino acids 314 to 333 (20 residues), see Phobius details amino acids 338 to 357 (20 residues), see Phobius details amino acids 366 to 389 (24 residues), see Phobius details PF01957: NfeD" amino acids 375 to 462 (88 residues), 60.4 bits, see alignment E=9.8e-21

Best Hits

KEGG orthology group: K07403, membrane-bound serine protease (ClpP class) (inferred from 100% identity to rso:RSc0803)

Predicted SEED Role

"Putative membrane-bound ClpP-class protease associated with aq_911" in subsystem YbbK

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y187 at UniProt or InterPro

Protein Sequence (470 amino acids)

>RS_RS04035 serine protease (Ralstonia solanacearum GMI1000)
MRPSLRIRQWIGWLAAGLAAAWSGLAIAAAAPVMVLPLTGAIGPASAAYVVHGLELARKE
GMQLVVLQMDTPGGLDASMRQIIQAILASPVPVAGYVAPGGARAASAGTYILYASHIAAM
APATNLGAASPVAIGIGGHAPTGPTPTPGDTAKPASAPAAASGNEDTLARKQMHDAAAYI
RGLAHLRGRNAEWAERAVREAVSLSADEAATQRVIDLIATNIPDLLRQVDGRALRTATGL
VTLHTAGAPTETLEPDWRNHFLAVITDPSLALLLLTVGVYALIFEFSTPGMVVPGILGAM
CILVALYGLQMLPINYAGLALLALGLGCMVAEAFLPTFGALGVGGIIAFILGAVMLIDTQ
TPGYGVPIPVIVGLAFVSLTVILALSSLAVRARRRPKVSGGDTLIGMTGEVVDVDTPEAD
ADSDGWAHIRGERWRVRCDAGITRGDRVRVIARHGLTLMVEPVAPAAAAS