Protein Info for RS_RS03595 in Ralstonia solanacearum GMI1000

Annotation: riboflavin synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00187: riboflavin synthase, alpha subunit
  • amino acids 1 to 204 (204 residues), 170.9 bits, E=1e-54
• PF00677: Lum_binding
  • amino acids 3 to 89 (87 residues), 49.3 bits, E=2e-17
  • amino acids 102 to 190 (89 residues), 85 bits, E=1.5e-28

Best Hits

KEGG orthology group: K00793, riboflavin synthase [EC: 2.5.1.9] (inferred from 100% identity to rso:RSc0714)

Predicted SEED Role

"Riboflavin synthase eubacterial/eukaryotic (EC 2.5.1.9)" (EC 2.5.1.9)

MetaCyc Pathways

• flavin biosynthesis I (bacteria and plants) (8/9 steps found)
• flavin biosynthesis III (fungi) (7/9 steps found)
• flavin biosynthesis II (archaea) (5/10 steps found)

KEGG Metabolic Maps

• Riboflavin metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.9

Sequence Analysis Tools

See Q8Y1H6 at UniProt or InterPro

Protein Sequence (217 amino acids)

>RS_RS03595 riboflavin synthase (Ralstonia solanacearum GMI1000)
MFTGIVAAIGRIETVEPLAADAQAGVRLGIHAGGLPLADVALGDSIAIQGACMTVVAKND
THFDVDVSRESLSKTVGLDRPGEVNLEKALRLADHIGGHLVSGHVDGLGTVSHFAPVGES
YELRVRTSPELGRYFAYKGSVVVNGVSLTVNSVRDDATGCEFSINLIPHTLAVTTLKHLA
VGGQVNLEIDLIARYVERMLTHTATGLPAAARPLAAV