Protein Info for RS_RS03235 in Ralstonia solanacearum GMI1000
Annotation: DUF898 domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to rso:RSc0643)Predicted SEED Role
"Thymidylate kinase (EC 2.7.4.9)" (EC 2.7.4.9)
MetaCyc Pathways
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (18/18 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis I (9/9 steps found)
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis III (8/9 steps found)
- pyrimidine deoxyribonucleotide phosphorylation (4/4 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis IV (6/7 steps found)
- pyrimidine deoxyribonucleotides biosynthesis from CTP (6/8 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)
- superpathway of pyrimidine deoxyribonucleoside salvage (5/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.4.9
Use Curated BLAST to search for 2.7.4.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q8Y1P7 at UniProt or InterPro
Protein Sequence (358 amino acids)
>RS_RS03235 DUF898 domain-containing protein (Ralstonia solanacearum GMI1000) MNDIAREPVLGGAPAPAVPQPLRVRFCGSGSEYFRIWIVNLLLTIVTLGIYSAWAKVRTL QYFYRNTQLGGASFDYHGSPTAILKGRAIIFVLALAFNLSGQVSPVLTLLLLAAIGLVFP WLLVRSLRFRMANSSYRGLRFAFTGKDAQAYKVFLLWPVLTVFTFNLLAPFAHQRFKQYQ HRNTRFGTTSFDFSATAGQFYGVYLRTFGMAILAVMAVGVVVVLAGVSAAAGAASGGRAI AVSLMVLAMYAAMLFLGPYFLARLQNVVWNHTTLGAHRFQSQVSAGKLFWIFISNAALLI VTLGLFTPFARVRSARYKLESVTMLAAGSLDTFVAGESTRVGALGDAAVDWYDIDIAL