Protein Info for RS_RS02570 in Ralstonia solanacearum GMI1000

Annotation: chaperone SurA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details PF09312: SurA_N" amino acids 87 to 204 (118 residues), 138.5 bits, see alignment E=3e-44 PF13624: SurA_N_3" amino acids 89 to 203 (115 residues), 49.8 bits, see alignment E=9.1e-17 PF13616: Rotamase_3" amino acids 235 to 339 (105 residues), 70.1 bits, see alignment E=6.2e-23 amino acids 347 to 447 (101 residues), 85.1 bits, see alignment E=1.4e-27 PF13145: Rotamase_2" amino acids 240 to 340 (101 residues), 33.1 bits, see alignment E=2.2e-11 amino acids 359 to 454 (96 residues), 30.9 bits, see alignment E=1.1e-10 PF00639: Rotamase" amino acids 243 to 336 (94 residues), 73 bits, see alignment E=8.6e-24 amino acids 356 to 446 (91 residues), 81.2 bits, see alignment E=2.4e-26

Best Hits

Swiss-Prot: 100% identical to SURA_RALSO: Chaperone SurA (surA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03771, peptidyl-prolyl cis-trans isomerase SurA [EC: 5.2.1.8] (inferred from 100% identity to rso:RSc0516)

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y220 at UniProt or InterPro

Protein Sequence (496 amino acids)

>RS_RS02570 chaperone SurA (Ralstonia solanacearum GMI1000)
MACKSTAVRSATRVAPTRRLGMVTGALVALMAGAALLPAAHAQQTQKKSAPLRGIFTTPD
ASPSQPLLRGTLPGPSTASGAARSQLVDEVVAVVNTDIITRRELLDRADLVERTLQSQNR
QVPVRADLLGEVLEQLILERVQAQTAKESGIRVSDADVDRAVESVAQRNNLSVSQLKSKL
AQSGLAYDKYREDLRQEILLARLRDREVDSKVQVFDGEIDNFLAQQGGSAASSGVQEYNV
AQILVPVAEDASAEQKAAARGKAESLLKQVQGGADFAKLARDSSGAPEAAQGGELGLRPI
GRLPAQFANAVVDLKPGQVVDQVIESPAGFHVLKLVDKRAQGTAITAKVAQTQVRHILIK
TGPTMSADDARRQLAGLRDRIVHGYDFGDAARRYSQDTSASAGGELGWVSPGQLVPEFEQ
AMGLLKPGEVSQPVQSQFGLHLIQVEGRREAEVPVDRQRDYARSVIREQKVQAAYEDWLR
QLRDSAHVEYRVNRQQ