Protein Info for RS_RS02080 in Ralstonia solanacearum GMI1000

Annotation: excinuclease ABC subunit UvrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 954 TIGR00630: excinuclease ABC subunit A" amino acids 4 to 936 (933 residues), 1450.4 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 130 to 247 (118 residues), 108.5 bits, see alignment E=6.4e-35 PF17755: UvrA_DNA-bind" amino acids 298 to 407 (110 residues), 126.6 bits, see alignment E=2.2e-40

Best Hits

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y2B6 at UniProt or InterPro

Protein Sequence (954 amino acids)

>RS_RS02080 excinuclease ABC subunit UvrA (Ralstonia solanacearum GMI1000)
MEAIKIRGARTHNLKNINLDLPRNQLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY
ARQFLQLMEKPDVDLIEGLSPAISIEQKATSHNPRSTVGTVTEIHDYLRLLYARAGTPYC
PEHGQPLEAQSVSQMVDAVLALPADTKLMILAPVVTNRKGEHVDLFEAMQAQGFVRFRIR
SGGGTAHEAEAKVYEVDALPKLKKNDKHAIEVVVDRVKVNPELKQRLAESFETALRLADG
RALALEMDTGKEHVFSSKFACPICSYSLPELEPRLFSFNNPMGACPHCDGLGQITFFDPK
RVVAFPNLSLASGAIKGWDRRNQFYFQMLQSLAAFYDFDTDTPFEELPSEVQDVVLQGSG
KQQIPFTYINERGRTTVREHAFEGIIPNLERRYKETDSIAVREELAKYQNNQACPECEGT
RLRREARHVKLGDSDQARAIYEINGWPLRDALTYFLTLNLHGAKREIADKIVQEITSRLN
FLNNVGLDYLSLERSADTLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLI
GTLKHLRDLGNSVLVVEHDEDMIRASDHVVDIGPGAGVHGGQIIAEGTPRQIERSPGSLT
GEYLSGKRRIEVPKQRTAPDEARWLRIVNASGNNLKHVNADIPVGLLTCVTGVSGSGKST
LINDTLYNAVARHLYGSTPEPTAHDRIDGLEHFDKVINVDQSPIGRTPRSNPATYTGLFT
PIRELYAGVPAAKERGYDPGRFSFNVKGGRCEACQGDGVLKVEMHFLPDVYVPCDVCHGK
RYNRETLEVLYKGKNITEVLEMTVEQAHEFFAPVPVVRRKLQTLLDVGLGYIRLGQSATT
LSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIELLLKVIHKLRDQGNTVVIIE
HNLDVIKTADWLLDLGPEGGAGGGQIIAKGTPEEVAKSRASFTGKYLAPLLKRK