Protein Info for RS_RS00595 in Ralstonia solanacearum GMI1000

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 PF18158: AidB_N" amino acids 11 to 165 (155 residues), 173.9 bits, see alignment E=5.1e-55 PF02770: Acyl-CoA_dh_M" amino acids 180 to 284 (105 residues), 53.9 bits, see alignment E=3.2e-18 PF00441: Acyl-CoA_dh_1" amino acids 295 to 450 (156 residues), 114.1 bits, see alignment E=1.4e-36 PF08028: Acyl-CoA_dh_2" amino acids 320 to 433 (114 residues), 49.4 bits, see alignment E=1.1e-16

Best Hits

KEGG orthology group: K09456, putative acyl-CoA dehydrogenase (inferred from 100% identity to rso:RSc0121)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y360 at UniProt or InterPro

Protein Sequence (557 amino acids)

>RS_RS00595 acyl-CoA dehydrogenase (Ralstonia solanacearum GMI1000)
MPADATHRVFNQVPDLAHFNPFTSDATLQGALGRLGGGWHADALRAFGETLGSPRTLAWA
AEANRYPPELHTHSRTGERIDSVRFDPAWHALLGLMRGQGLQALPFAEPRAGAWAARTAG
YFMQAQIESGSLCPATMTFASIPVLQKETALFADLAPRLYAREHDARDLPWRQKTAILVG
MGMTEKQGGSDVRSNTTVAVPLGGKDGGEGRGATYALTGHKWFFSAPMCDAHLVVARMGA
EDGPLSCFFVPRWRDDGGKNPVQIQRLKDKLGNCSNASSEVEFRAAQGILIGEAGRGIPT
ILEMATHTRLDCVIGSAALLRHALMQALHHARHRMAFGRLLADQPLMRNVLADLALESQA
ATLLMMALGDAFERAEADPVAAAWKRIVTPAAKFWVCKRAIEATGEAMEVWGGNGYVEEG
PMARLYREAPVNSIWEGSGNVMCLDVLRAIGRVPDDALRLVQDIGERARGHRAVRAELAA
LQAMLHQSGDIQEASARRIAQGLALTAQAALMLAHAHADDAERFIASRFHHQHGRVFGTL
EGNAQELGAALQRAWPA