Protein Info for RS_RS00310 in Ralstonia solanacearum GMI1000

Annotation: penicillin-binding protein 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 801 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details TIGR03423: penicillin-binding protein 2" amino acids 17 to 627 (611 residues), 797.1 bits, see alignment E=5.3e-244 PF03717: PBP_dimer" amino acids 61 to 251 (191 residues), 156.7 bits, see alignment E=9.2e-50 PF00905: Transpeptidase" amino acids 283 to 622 (340 residues), 212 bits, see alignment E=1.2e-66

Best Hits

KEGG orthology group: K05515, penicillin-binding protein 2 (inferred from 100% identity to rso:RSc0062)

Predicted SEED Role

"Penicillin-binding protein 2 (PBP-2)" in subsystem Peptidoglycan Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y3B8 at UniProt or InterPro

Protein Sequence (801 amino acids)

>RS_RS00310 penicillin-binding protein 2 (Ralstonia solanacearum GMI1000)
MTEIRNVEQELSRFRVRLAAAALFVLVCFGLLLVRFFWLQSVKHEQYSAKAEDNRISVAP
IEPNRGIIMDRNGVVLARNYSAYTLEVTPSKLQDTLDNTIDQLAQVIDIQPRDRRRFKRL
MEDARSFESLPIRSQLTDQEVARFSAQRFRFPGVDVHARLFRQYPLGEAAAHVIGYIGRI
SERDLERIDDMSEANSQPNVTYDPRKDANNYSGTEYIGKVGIEQSYETELHGLTGYEEVE
VSAGGRPIRTLSTSQATPGNNLILSLDINLQRLAEQLFGNRRGALVAIEPETGDILAFVS
KPTFDPNLFIEGIDSATWSELNGSPDKPLLNRPLRGTYPPGSTYKPFMALAALELGKRTP
QWGMADPGSFTLGNHTFRDDVPGGHGWVDMYRSIVVSCDTYYYKLANDMGVNAIHDFMKP
LGFGQVTGIDIEGERTGILPSTEWKRKAYKRPEQQKWYDGETISLGIGQGYNNFTILQLA
HAVATLANNGGVMKPHLVKAVEDSVNKARTLTVPTESYRIPLKQANIDVIKRAMAGVVQA
GTAAKAFAGAQYAAAGKTGTAQVFSLGKGEKYNHHAIPEYKRDHALFEAFAPTDHPKIAV
ALIVENAGFGATSAAPIARAVFDYYLQGKWPAELAAIAPKVQPQPPVDTPSVFSTGKTAT
IASATATPQAAAEAVAQSAALAAAASGEQAADAATVGGASAPGASAVAAGAPRAAPAMSS
DRVAPALREAGTSAQAVAPATLDAQVLQALSHVQPAPDLPSPRGRNLPAAPASAPAASPK
DRKPAVKPNPKPAPKPARAAP