Protein Info for RS_RS00015 in Ralstonia solanacearum GMI1000

Annotation: membrane protein insertase YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 553 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 363 to 383 (21 residues), see Phobius details amino acids 428 to 450 (23 residues), see Phobius details amino acids 473 to 490 (18 residues), see Phobius details amino acids 503 to 526 (24 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 4 to 361 (358 residues), 363.9 bits, see alignment E=1.3e-112 PF14849: YidC_periplas" amino acids 84 to 352 (269 residues), 280.2 bits, see alignment E=2.8e-87 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 362 to 541 (180 residues), 249.3 bits, see alignment E=3e-78 PF02096: 60KD_IMP" amino acids 363 to 541 (179 residues), 228.6 bits, see alignment E=4.1e-72

Best Hits

Swiss-Prot: 100% identical to YIDC_RALSO: Membrane protein insertase YidC (yidC) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 100% identity to rso:RSc0004)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y3H6 at UniProt or InterPro

Protein Sequence (553 amino acids)

>RS_RS00015 membrane protein insertase YidC (Ralstonia solanacearum GMI1000)
MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAA
PAAAGSQAAPATGAVSQTPASEKIVVTTDVIRATVDTAGAIVTKLELLTQKDHDGNPMVL
FDRSLERTYLARSGLIGGDFPNHTTVFTASAGPRDLGTGGEVSLTLTADKGGAKLAKTYV
FKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYSTFTGPAVYTDTDHYHK
ITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREFYVDRIDTNFYRVGMQQA
LGTVAPGASVSATARLFAGPQEERMLEGITPGLELVKDYGWLTIIAKPLFWLLEKIHKLL
GNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMTAIRERHKGDPQKMNQEMMTL
YRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWVHDLASPDPFYILPILM
AVSMFVQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSIN
RMLGTNKKAAAAK