Protein Info for RR42_RS37340 in Cupriavidus basilensis FW507-4G11

Annotation: cellulose synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 45 to 62 (18 residues), see Phobius details amino acids 69 to 87 (19 residues), see Phobius details amino acids 102 to 124 (23 residues), see Phobius details amino acids 395 to 443 (49 residues), see Phobius details amino acids 464 to 485 (22 residues), see Phobius details amino acids 511 to 531 (21 residues), see Phobius details amino acids 540 to 561 (22 residues), see Phobius details amino acids 683 to 702 (20 residues), see Phobius details TIGR03030: cellulose synthase catalytic subunit (UDP-forming)" amino acids 23 to 699 (677 residues), 921.7 bits, see alignment E=1.3e-281 PF13641: Glyco_tranf_2_3" amino acids 145 to 372 (228 residues), 58.8 bits, see alignment E=2.5e-19 PF00535: Glycos_transf_2" amino acids 149 to 317 (169 residues), 76.6 bits, see alignment E=6.7e-25 PF13506: Glyco_transf_21" amino acids 209 to 371 (163 residues), 24.1 bits, see alignment E=7e-09 PF13632: Glyco_trans_2_3" amino acids 227 to 434 (208 residues), 65.4 bits, see alignment E=1.9e-21 PF03552: Cellulose_synt" amino acids 323 to 444 (122 residues), 33.5 bits, see alignment E=5.8e-12 PF07238: PilZ" amino acids 566 to 662 (97 residues), 44.8 bits, see alignment E=4e-15

Best Hits

Swiss-Prot: 60% identical to BCSA_PSEFS: Cellulose synthase catalytic subunit [UDP-forming] (bcsA) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K00694, cellulose synthase (UDP-forming) [EC: 2.4.1.12] (inferred from 63% identity to bge:BC1002_3564)

Predicted SEED Role

"Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.12

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YGP2 at UniProt or InterPro

Protein Sequence (720 amino acids)

>RR42_RS37340 cellulose synthase (Cupriavidus basilensis FW507-4G11)
MSAALQRFGNTFVALPFWDSAVARLLALLAGLFMFALVITVPLDFWQQVGFAAVCFGLAV
WLNRVKGHLATLMMVILSIAASSRYMYWRLTETVGLGGWFDSAFGIGLVLAEIYAFVVLM
LGYFQTAWPLKRRPVAMPADIASWPTVDIFIPTYNEPLSVVKPTVFAAMSLDWPRDKINV
YVLDDGRREEFREFCEKVGVTHVTRNHNRHAKAGNINEALKGTHGEYVAIFDCDHIPTRS
FLQISMGWFLKDPKLAMLQTPHYFFSPDPFEKNLRTFQEVPNEGELFYGLVQDGNDLWDA
TFFCGSCAVIRRAPLLEVGGIAVETVTEDAHTALKLHRKGYGTAYLAIPQAAGLATESLS
GHVGQRIRWARGMAQICRVDNPLFGPGLSIPQRLCYLNAMLHFFYGLPRLVFLTAPLAYL
LFGAHVIQASALTIATFALPHLLHANMTNSRIQGKFRHSFWNEVYESVLAWYIMRPVLVA
FVNPAAGKFNVTPKGGVIEEAYFDWVISRPYLVLLLFNVLGVVVGFLRLFLWNQFEATTV
VLNLIWTFYNLIILGASIAVASETRQIRVAHRVAMKLPATLHFPDGRTLVCETIDFAEGG
IGMRLPPGMKAAVGEQVQISLYLQNDEHMFPAKVVFQGDTHTGLELAEMSPREEMAFVQC
TFARADAWIDSWGRKRPDAPGLAAGQILRIGLLGFHNVMFHLGREMRQLLRRPEPGASTR