Protein Info for RR42_RS36205 in Cupriavidus basilensis FW507-4G11
Annotation: amidase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01426, amidase [EC: 3.5.1.4] (inferred from 73% identity to reh:H16_B1874)Predicted SEED Role
"Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases"
MetaCyc Pathways
- superpathway of acrylonitrile degradation (3/3 steps found)
- acrylonitrile degradation I (2/2 steps found)
- indole-3-acetate biosynthesis IV (bacteria) (2/2 steps found)
- L-arginine degradation X (arginine monooxygenase pathway) (2/3 steps found)
- indole-3-acetate biosynthesis III (bacteria) (1/2 steps found)
- indole-3-acetate biosynthesis II (6/12 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- Benzoate degradation via CoA ligation
- Biosynthesis of plant hormones
- Cyanoamino acid metabolism
- Phenylalanine metabolism
- Styrene degradation
- Tryptophan metabolism
- Urea cycle and metabolism of amino groups
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.4
Use Curated BLAST to search for 3.5.1.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0C4YG35 at UniProt or InterPro
Protein Sequence (502 amino acids)
>RR42_RS36205 amidase (Cupriavidus basilensis FW507-4G11) MTRQDIASTDTRPPKARFLPVWEAAALLAKGDTSAQDLVNWCEAAYAASHREINALILAD FSAARAAAEASDQRRRRGEPLGLLDGIPYSIKESFDVAGWPTTCGNPAQRHNIAISDSAV VERLRAAGAVLLGKTNVPIGLRDWQSYNAIYGTTRNPRDPGRTPGGSSGGSAAAVCAGMS FFDVGSDIGSSLRNPAHYCGVFSHKSSHGLVPLRGHGIGHGYGEQEINVAGPLARSAHDL ELLLRALAGPDGIEAQAYRLTLPPCDKRTLADFRVAVLPSHPLCEADGEVSDEIEKLGRW LEGQGAQVRWNARPDFDASALWHTYVLMLRATTSIHMDDAGFDAALARAAGAAPDDHSYA TLQFTGAGIRHRQWLQLQQARATFAQAWQRFFGEVDVLLCPAAATTAFVLDEAGEPWQRM LQVNGRAQPLTSQLFWAGHSGLCGLPSTVAPIGPGRSGLPVGVQIVAGKFEDLTTLRFAQ LLEAAGFAFRPPPASAQSQSQS