Protein Info for RR42_RS35550 in Cupriavidus basilensis FW507-4G11

Annotation: chemotaxis protein CheY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 PF00072: Response_reg" amino acids 6 to 118 (113 residues), 82 bits, see alignment E=3.5e-27 PF00486: Trans_reg_C" amino acids 158 to 230 (73 residues), 94.4 bits, see alignment E=3.6e-31

Best Hits

Swiss-Prot: 47% identical to PHOB_SHIFL: Phosphate regulon transcriptional regulatory protein PhoB (phoB) from Shigella flexneri

KEGG orthology group: K07657, two-component system, OmpR family, phosphate regulon response regulator PhoB (inferred from 58% identity to bge:BC1002_2084)

Predicted SEED Role

"Phosphate regulon transcriptional regulatory protein PhoB (SphR)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YRY8 at UniProt or InterPro

Protein Sequence (230 amino acids)

>RR42_RS35550 chemotaxis protein CheY (Cupriavidus basilensis FW507-4G11)
MARKTVLVIDDDPAICEIIAINLRAAGLIPLSAHDSLAANRLICEASPDLILLDWMLPGQ
PVLSFARELRNNHHTKNTGIIMLAASSEEADVIAGLEAGADDYVTKPFSPRELVARIRTL
LRRRAPEWTNDVTVIGPLTLNLASRRVFVASEDTEEILDFGPTEFTLLHYLMNHPERVHS
RAQLLDSVWGDQRYVDDRTVDVYIKHLRARLSKVNLSDLIQTVRGVGYRL