Protein Info for RR42_RS34270 in Cupriavidus basilensis FW507-4G11

Annotation: Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 641 PF01590: GAF" amino acids 67 to 195 (129 residues), 49 bits, see alignment E=2.8e-16 PF00158: Sigma54_activat" amino acids 322 to 485 (164 residues), 220.7 bits, see alignment E=2.9e-69 PF14532: Sigma54_activ_2" amino acids 325 to 490 (166 residues), 71.9 bits, see alignment E=2e-23 PF07728: AAA_5" amino acids 342 to 455 (114 residues), 23.3 bits, see alignment E=1.7e-08 PF02954: HTH_8" amino acids 601 to 640 (40 residues), 54 bits, see alignment 3.4e-18

Best Hits

KEGG orthology group: None (inferred from 67% identity to bph:Bphy_3427)

Predicted SEED Role

"Nitrogen regulation protein NR(I)" in subsystem Ammonia assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YUY6 at UniProt or InterPro

Protein Sequence (641 amino acids)

>RR42_RS34270 Fis family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MSSTLASHAATPHADPERHILIARAHARSTGFGLEATHAADYQSLGARALHELVDANQML
YKHALPVMETLHAQIANTESMVLLTDSGGVILHSLGDGDFADRARRVALAPGVSWAESSK
GTNAIGTALAEARPAVVHADEHFLRANRTLTCSCVPISGPFGQMLGALDVSGDHRGFHKH
TMALVRMSAQMIENHLFSTHFTDAALVRFHARPEFVGTLFEGMAAFAPDGTFLAANRSGL
FQLGLSPDTLNRQSFAALFGMPLGTALKQGVDAPGQLLTLTLPSRVLVFARIALLAPPRR
AQAARATKSATTSALAALDTGDARMAAVLQRVDKVRGRDIPILVLGRTGTGKEWLARAIH
RDSPRGAAPFVAVNCASIPESLIEAELFGYEDGAFTGARRRGSPGKLVQAHGGTLFLDEI
GDMPLAQQVRLMRVLQERAVTPLGGAHAIPVDLRIICATHRDLRAMIAAGTFREDLYYRI
NALSVTLPALRERTDLPVLVERILTQQLAQAEHGDAHPTRVAADVLAHFQRHPWPGNLRQ
MVNVLRTAAIMAEGEEEIRVEHLPEDFEREPMFAQDSDAASAFMPPTPVMPVTPAGTPER
LRDREAAMIHQALARHGGNVSLAARELGLSRNTIYRRLKRS