Protein Info for RR42_RS33085 in Cupriavidus basilensis FW507-4G11

Annotation: ligand-gated channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 739 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF07715: Plug" amino acids 70 to 169 (100 residues), 78.1 bits, see alignment E=6.9e-26 TIGR01783: TonB-dependent siderophore receptor" amino acids 72 to 738 (667 residues), 284.9 bits, see alignment E=7.9e-89 PF00593: TonB_dep_Rec_b-barrel" amino acids 245 to 709 (465 residues), 201.3 bits, see alignment E=5.5e-63

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 84% identity to rme:Rmet_4617)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YNU8 at UniProt or InterPro

Protein Sequence (739 amino acids)

>RR42_RS33085 ligand-gated channel protein (Cupriavidus basilensis FW507-4G11)
MTAPLKTRARLLASAGAIYCTGFLAATPAFAQSAADAGNAKEATLPTAVVTADSPLQAKR
LPSYKFVAPLLDTPRSVTVIPEELLKQTNATTFADALKTVPGITFLGGDAAANPSADRPV
IRGFESRNSIFVDGMRDSGVQNRETFAVEQISVIKGPDSVYAGRGAVGGSIDIVTKMPKA
DDFTNASLGLGTEAYKRATLDVNRRLNDETAVRLNVMGHDANQAGRNDVYSKRWGVAPSV
AFGLNTPTTVSLSYYHVNTYDMPDFSVPFRSTGGTPGAGTSIQRSQFYGLNNRDYRRGQT
DTGEIRIEHRVDDNWKVRNTTMFGRSTLDYIATNPQFLNASANLLQLQAKSGKYATNSVS
NQTELSGKATLLGMQHTLTAGVEFSWERSLYEGYLVSDSAGNNIRTGGPCTIAYNCTAIG
AWNANAPWTGSTVLNADKSFPGAPTSTRTNVSSAYLFDSVKLSDRWLFNAGTRFDRFDVT
AVQAGTPDLKNTANLFSYQLGLVFKPIDTVSLYASYGTSANPPGANSGLGGGTDQITKTN
QDLSPERSRNIEVGAKWDTLDRRLSLTSALFQTDKTNARVSDGLGGIVNAGKQRVRGAEL
GMAGNLTSKWRVFGGYSYLDAITIDAGSANASASGLPMVMVPKHNVTLWTYYDVLPRLSI
GGGATISSLTYASVSATSRKWTPGYARFDAVATYRVSKTVDVQLNVQNLFDKKYYSAAYP
IYATWAPGRSVVMTLNFHM