Protein Info for RR42_RS32825 in Cupriavidus basilensis FW507-4G11

Annotation: ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 878 transmembrane" amino acids 65 to 84 (20 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 254 to 271 (18 residues), see Phobius details amino acids 279 to 305 (27 residues), see Phobius details amino acids 693 to 718 (26 residues), see Phobius details amino acids 754 to 778 (25 residues), see Phobius details amino acids 784 to 803 (20 residues), see Phobius details amino acids 819 to 844 (26 residues), see Phobius details amino acids 853 to 869 (17 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 12 to 80 (69 residues), 59.4 bits, see alignment 5.5e-20 TIGR01494: HAD ATPase, P-type, family IC" amino acids 92 to 189 (98 residues), 62.8 bits, see alignment E=1.1e-21 amino acids 222 to 354 (133 residues), 98.4 bits, see alignment E=1.7e-32 amino acids 592 to 711 (120 residues), 107.4 bits, see alignment E=3.1e-35 PF00122: E1-E2_ATPase" amino acids 120 to 311 (192 residues), 173.8 bits, see alignment E=6.8e-55 PF00702: Hydrolase" amino acids 330 to 634 (305 residues), 61.9 bits, see alignment E=2.8e-20 PF13246: Cation_ATPase" amino acids 376 to 460 (85 residues), 68.2 bits, see alignment E=1.3e-22 PF00689: Cation_ATPase_C" amino acids 705 to 874 (170 residues), 188.3 bits, see alignment E=2.7e-59

Best Hits

KEGG orthology group: K01537, Ca2+-transporting ATPase [EC: 3.6.3.8] (inferred from 70% identity to rfr:Rfer_1665)

Predicted SEED Role

"Cation-transporting ATPase"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YU19 at UniProt or InterPro

Protein Sequence (878 amino acids)

>RR42_RS32825 ATPase (Cupriavidus basilensis FW507-4G11)
MKPASTPSVSGWHLRDARELAREQGVDPAQGLSEDEARLRAGRHGPNALQETSGRGLLSL
VAAQCKDFMVIVLLAAAIASGVIGDLSDTLAILMILLLNAAIGIAQAWRADRAIAALRQL
AAAQATVLRGGHLETVPASVLVPGDIVQLEAGNHIPADLRLIEVAQLQVDESALTGESVA
VAKQSVAMSANSSAFLADRLNMAFKGTVATHGRGTGIVMATGMATELGKVARLLDTAERS
TPLQRRLAGFGRRLSIAVLGICLVIFGLGVLRGEGLLPMALTAISLAVAAIPEALPAVVT
VLLALGARRMAAVHALVRRLPSVETLGSVTTICSDKTGTLTQNRMQVELLLANGRQWVPG
DSLPGVVHREALLAAVLCNDARQSGGDTPGDWQGDPTETALVRAGLSGGIDKAAMDEALP
RVQEQPFDSGRKRMTTVHSGAHDYVAYTKGAPESVLPCCEARWTPDGPAPLDSANVLEQA
NTLAGQGLRVLALARRNHPRLPDANALAEVECRLQFLGLLALIDPPRLEAADAVRDCIGA
GITPVMITGDHPATARAIAYRLGIVPERDAEVVTGVDLASLDDTALRERVARARVFARVD
PAQKIRIVEALQARGEFVAMTGDGVNDAPALKRAEIGVAMGKNGTDVARESSSLVLLDDN
FATIVAAVREGRRIYDNIRKFVRYAMTGNSGEIWTIALAPLFLLPIPLLPIHILWINLVT
DGLPGLALAAEPAESGIMRRPPRPPTESLFAHGMWQHIVSIGLLIAGLCLGVQAWALAGG
QRHWQTMVFTVLTLSQMAHVLAIRSEQTPLWRLGLRSNLPLLAAVLLTFGLQLAAIYVPI
LNMIFKTEPLGPQDLGICLGASSVAGIAVEIEKAWRRR