Protein Info for RR42_RS32565 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 57 to 76 (20 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 145 to 170 (26 residues), see Phobius details amino acids 176 to 195 (20 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details amino acids 293 to 313 (21 residues), see Phobius details amino acids 320 to 339 (20 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 385 to 405 (21 residues), see Phobius details amino acids 411 to 430 (20 residues), see Phobius details PF07690: MFS_1" amino acids 27 to 382 (356 residues), 151.8 bits, see alignment E=2.4e-48 amino acids 299 to 435 (137 residues), 42 bits, see alignment E=6e-15 PF00083: Sugar_tr" amino acids 42 to 426 (385 residues), 80.2 bits, see alignment E=1.6e-26

Best Hits

KEGG orthology group: None (inferred from 63% identity to vap:Vapar_5692)

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YPT7 at UniProt or InterPro

Protein Sequence (445 amino acids)

>RR42_RS32565 MFS transporter (Cupriavidus basilensis FW507-4G11)
MKLDIRETINQGEMSRFQIMAVAICIVLNMLDGFDVLAMAFTASHISSDWHLSGKEIGVL
LSAGLFGMAAGSLFLAPWADRLGRRPVILLCLVTISAGMLWSAFAQSVTQLAAMRAITGL
GIGGMLASINVITGEYASDKWRSTAIVLQATGYPVGATIGGAIAGVLLLHYGWRSVFVFG
GLVTLVMIPVVLARLPESLDFLIARRPAGAVDKLNKLLAGMGRERITEMPARAAAQTPAQ
GGVRSLFGGRLAMPTLMIWTSFFLVMFSFYFVLSWTPKLLVAAGMSAQQGITGGVLLNVG
GIVGGTLFGFLAARIGLKPLLWTCFVLTALLLVAFGLYANTLSVAFVLALFIGGGIFGCM
VGLYAYAPILYPAQNRTTGMGWSIGMGRFGAVLAPLVAGALVDAGWPTSNLYYVFALPLL
VAIASVGLLGRSPAADGQAVRIAAH