Protein Info for RR42_RS31420 in Cupriavidus basilensis FW507-4G11

Annotation: LuxR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 transmembrane" amino acids 43 to 58 (16 residues), see Phobius details PF00072: Response_reg" amino acids 19 to 128 (110 residues), 94.6 bits, see alignment E=6.4e-31 PF08281: Sigma70_r4_2" amino acids 153 to 197 (45 residues), 26.3 bits, see alignment 7.1e-10 PF00196: GerE" amino acids 153 to 208 (56 residues), 68 bits, see alignment E=6.5e-23

Best Hits

Swiss-Prot: 54% identical to NODW_BRADU: Nodulation protein W (nodW) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: None (inferred from 74% identity to cti:RALTA_B0395)

Predicted SEED Role

"two component transcriptional regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>RR42_RS31420 LuxR family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MTINSFVTADTSASDEAMVLIVDDDAMLRGALENLFRSVGMRVALFASAAELLAFALPDV
PTCLLLDVRLRGQSGLDLQTQLSQMGVQVPIIFMTGYGDIPMTVTAMKAGAEDFLAKPFR
EQDLLDAVAAALQKDQHRRHGMRKLDELRSGYQSLTPREAEVMRMVVAGLLNKRIASELS
ISEVTVKIHRGQAMRKMKARTFAGFVLMAQQLGICPH