Protein Info for RR42_RS31060 in Cupriavidus basilensis FW507-4G11

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 274 to 296 (23 residues), see Phobius details PF02743: dCache_1" amino acids 37 to 260 (224 residues), 77 bits, see alignment E=2.3e-25 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 354 to 510 (157 residues), 155.9 bits, see alignment E=4e-50 PF00990: GGDEF" amino acids 359 to 508 (150 residues), 139.2 bits, see alignment E=1.7e-44

Best Hits

KEGG orthology group: None (inferred from 66% identity to rsl:RPSI07_1500)

Predicted SEED Role

"PROBABLE TRANSMEMBRANE PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YMC4 at UniProt or InterPro

Protein Sequence (523 amino acids)

>RR42_RS31060 diguanylate cyclase (Cupriavidus basilensis FW507-4G11)
MGLGGLILLLALGSVLLTMANALYSSYRVQRDLLIRNTLEANRVYAAKLAQSTGAHLEST
MQQLAYSAGLLAAAMDNPARVDEEAERLRLQTRSLNSVAIVRQDGMVLSVSPAALRRSGQ
SVKTDWGHTLLSTRTPAISEPFTSASGRLIIFISHPIINAEGRLLGYVGGTIYLNAKNLL
HEILDNHYYRDSSYVYVVDRKGTVIFHPDDTHVGKSIFKNSVVLAVTSGAAGAQQILNQY
GVEMLAGYAPVASTGWGIVAQRSTQATLADLNDLVLVTFGNSIPILLLSLVFILWFSRWI
SRPLGQLADDARMGTTPDGMARIERIQARYVEADRLKKALLRGMSLTSSKLDRLNHESIT
DALTGLRNRRGLDNALSLYELGGQSFAVITLDVDHFKSINDRYGHDVGDEVLTHIASLMR
AGSRGGDMTCRNGGEEFVILLPGTTADNAFLIAERLREAVEKTPNPTGGVVTVSLGVAHF
PSSAEEVGEVLKKSDIALYQAKRNGRNNTVRYQPEPAVQADSP