Protein Info for RR42_RS31005 in Cupriavidus basilensis FW507-4G11

Annotation: homospermidine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF03435: Sacchrp_dh_NADP" amino acids 9 to 139 (131 residues), 71.3 bits, see alignment E=1e-23 PF16653: Sacchrp_dh_C" amino acids 149 to 416 (268 residues), 77.3 bits, see alignment E=2.1e-25

Best Hits

KEGG orthology group: K00808, homospermidine synthase [EC: 2.5.1.44] (inferred from 70% identity to reh:H16_A0043)

Predicted SEED Role

"Homospermidine synthase (EC 2.5.1.44)" (EC 2.5.1.44)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.44

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YNR7 at UniProt or InterPro

Protein Sequence (442 amino acids)

>RR42_RS31005 homospermidine synthase (Cupriavidus basilensis FW507-4G11)
MSSKRIEHIVIVGFGCIGQAILPLLAQAHPEAAVTVVDRAMDAHRLALARQYRATQLHAT
VAPDNFARVLSPLLGAQTCLLNLAPAVCSRDLIALAQAHHALYLDSGIEPWDYEDGAPSS
HLSNYALRSEMLAFARGRERMSTALVAHGANPGLVSLLAKAALLKLARHAGAPDTPPQDQ
AGWARLARRLDVRVIQVAEHDSQCAPGYPAHGEFANTWSADGFITECLQDAELGWGSHEP
ALPAGGRRHGYGSDAAIVLDRPGHRTRVRSWSALHGPFDAYLITHNESISIAEYFSCATP
CEPHYRPTAYYAYRPTRATMASMQWLGERDASRIASHRILKDEIVDGVDELGVLLMSGRH
GAVWHGSQLDIHRARALAPHNSATSLQVASSIVAAMRWAQANPARGVTESDAMDHHVVLE
HAAGWWAPLVTRFTDWTPRPGR