Protein Info for RR42_RS30800 in Cupriavidus basilensis FW507-4G11

Annotation: sugar ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 530 PF00005: ABC_tran" amino acids 22 to 170 (149 residues), 113.7 bits, see alignment E=5.4e-37 amino acids 282 to 426 (145 residues), 53.4 bits, see alignment E=2.2e-18

Best Hits

Swiss-Prot: 42% identical to YUFO_BACSU: Uncharacterized ABC transporter ATP-binding protein YufO (yufO) from Bacillus subtilis (strain 168)

KEGG orthology group: K02056, simple sugar transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 62% identity to bav:BAV3396)

Predicted SEED Role

"ABC transporter ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YSS4 at UniProt or InterPro

Protein Sequence (530 amino acids)

>RR42_RS30800 sugar ABC transporter ATP-binding protein (Cupriavidus basilensis FW507-4G11)
MPTPILRLAGITKRFGPLVANDDISLELQRGEVLALLGENGAGKSTLVSILFGHYVADAG
TVEVDGQPLPPGQPRAALTAGIGMVHQHFTLADNLSVLDNIMLGTQPLWQWRLDGHAARG
KVLALAERFGLAVRPQARVGELSVGERQRVEIVKALYRGARVLILDEPTAVLTPHEAETL
FSTLAQLIAEGLSVIFISHKLDEVLRVSDRIAVLRGGKLVALCAAAQTTKAELAELMVGR
VVAMPERVARRSAEDGANGNAAPPVLALEHVGARAANGRALLREVSLQVRAGEIVGIAGV
SGNGQAALAELASGMLEASEGRITLAGKPMSAKPRAWIGAGVARVPEDRHAIGVVGDLAV
WENAVSEQLSEPRFSRWGVIRRAAAQRFARDLVARFDVRTAGIDVPARTMSGGNMQKLIL
GRALSVRGEGSAPRLVVASQPTWGLDIGAVAYVRARLLDAAREGAAVLLISEDLDELHAL
ADRIAVMHAGHLTEARPTAAWTLGELGLAMAGSGGGQHAQAGKGEVLHAA