Protein Info for RR42_RS30665 in Cupriavidus basilensis FW507-4G11

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 703 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF07715: Plug" amino acids 68 to 176 (109 residues), 55.1 bits, see alignment E=1e-18 PF00593: TonB_dep_Rec_b-barrel" amino acids 316 to 664 (349 residues), 134.1 bits, see alignment E=1.3e-42

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 79% identity to reu:Reut_B4246)

Predicted SEED Role

"Outer membrane receptor proteins, mostly Fe transport" in subsystem Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YNM2 at UniProt or InterPro

Protein Sequence (703 amino acids)

>RR42_RS30665 TonB-dependent receptor (Cupriavidus basilensis FW507-4G11)
MKRARHWKQRTAALPAAAFATFTTAALAQAGAPATPDAAVTLPAATVTAKTPGSLTAPNV
QQQQQALDQTAGSVGFVDAASYSDTYASNLRDVLKDAPGVYVQERYGQELRLSIRGSGVA
RGYHARGLDLLQDGVPTNFADGSGDYYQIDPLGLSAAEIYKGGNGLAYGTTTLGGAINFT
TPTALTTDAPNQVRVDGGSFGTARASGQVSRQIGAFDFLANLSVNHSDGFRAHERGQYEQ
FNANFGYRLSPAVETRFYVGAYIVDQQLPGALSLTDALNNPKKAAPAALSGDQARNTRTE
RVANVTTIKLDSGQLDFSTWVIHKSLYHPIFQVIDQDYWTYGFAPRYTGTQTIGGLRNQL
IVGARFFGGNNDARQYVNNAGNRGAQTLNAAQDAYNYEAYLEDRLCLTPTIALMAGAKAY
RNVRRYQDDGGLPPNPTAKSASATYSGVNPKFGVLWEPVPDVQAFADITRSADVPDFTDL
SQTMATTTRFVPLSAQRGWTLELGTRGKRERFSWDVTAYRSLVRDQLLQYTTNPNIPAAT
FNANRTTLQGVELGVHGDVLQNLFGSGDKLTLSQLWNYSDFRFDNDPQYGNNRIAGIPKH
VLRTTVAYSRAAGLRVAATIDWVPGGAYVDYANTLRTPGYVLFGLQASYEFQRGVTVFLD
ARNLGNKRYVSDFSTVADARTANTAVFYPGSGRALYAGVKYKF