Protein Info for RR42_RS30645 in Cupriavidus basilensis FW507-4G11

Annotation: membrane protease subunit, stomatin/prohibitin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF01145: Band_7" amino acids 9 to 197 (189 residues), 48.7 bits, see alignment E=4.7e-17

Best Hits

KEGG orthology group: None (inferred from 73% identity to tmz:Tmz1t_0346)

Predicted SEED Role

"NrtR-regulated hypothetical NrtX, Band 7 protein domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YM60 at UniProt or InterPro

Protein Sequence (343 amino acids)

>RR42_RS30645 membrane protease subunit, stomatin/prohibitin (Cupriavidus basilensis FW507-4G11)
MFGIRFIKADPTTYLMQMQSGKIIREGSGQSFYYYAPTTSLVAVPVGSQILPYIFELITT
DFQSVTVQGNLSYRITEPRKTAAMLNFALKPDGRNYISEDPQNLRTRVEGVVEVLVQQAV
SVETLRCALQASDRMARQVEGALKAHPDVLALGLEILSFSMVAVKPRAETARALEAEVRE
QILKAADDAIYARRNAAVENERAIKESELDTEVAVELKQRTIRETQMEAEAAVQKKQAEL
EASTMEAQITLEARRKEFVGLEADNTRTTAEAEAHRLGAVMQALQGADARIVQALAASGM
APGQLIAQAFGGIADKAEKIGQLNMSPELLQSLLAPQSSSRPK