Protein Info for RR42_RS28400 in Cupriavidus basilensis FW507-4G11

Annotation: CoA-transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02515: CoA_transf_3
  • amino acids 4 to 368 (365 residues), 392.9 bits, E=7.7e-122

Best Hits

KEGG orthology group: None (inferred from 89% identity to reu:Reut_B4785)

MetaCyc: 39% identical to succinyl-CoA-glutarate CoA-transferase (Pseudomonas putida)
Succinate--hydroxymethylglutarate CoA-transferase. [EC: 2.8.3.13]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F"

MetaCyc Pathways

• L-lysine degradation X (4/6 steps found)
• L-lysine degradation IV (2/5 steps found)
• superpathway of L-lysine degradation (12/43 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.3.13

Sequence Analysis Tools

See A0A0C4YRG6 at UniProt or InterPro

Protein Sequence (391 amino acids)

>RR42_RS28400 CoA-transferase (Cupriavidus basilensis FW507-4G11)
MSRFTVIDASRVRAGPTAVRLFADMGARVIKLEIPPGAPGGDDMIGGRDHNRADYENLHR
NKESLTLNMKSPEGLKILHELVRRADVFIENFRPDVKDRLGIGPEALRVINPRLVYASIS
GFGQDGPYAGWPGFDSIAQGMGGLMSVTGKPGEGPMRVGIPIADLCAGHFCAMGILAALL
EREASGEGQWVQTSLLEAQIAMLDFQAAQWLIDKKVPVQSGNEHPLTVPTGVFATKDGYL
NIAAIGQTMWTRLCEALEVPHLIEEPGMGSDPERVQNRDKVNAAIQPALSARTTAEWTER
LLKAGVPCGPIHRVDQVFADPQVQHLGVAWPMHHAELGEVALVGQPMRLSRYPREQPPRA
APEQGADTSDILSELGYSAAQVAELRAAYVV