Protein Info for RR42_RS28090 in Cupriavidus basilensis FW507-4G11

Annotation: carbon-phosphorus lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 PF05845: PhnH" amino acids 15 to 201 (187 residues), 227.3 bits, see alignment E=6.8e-72 TIGR03292: phosphonate C-P lyase system protein PhnH" amino acids 16 to 200 (185 residues), 207.2 bits, see alignment E=8.9e-66

Best Hits

Swiss-Prot: 39% identical to PHNH_RHIME: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH (phnH) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K06165, PhnH protein (inferred from 61% identity to reu:Reut_B4187)

Predicted SEED Role

"PhnH protein" in subsystem Alkylphosphonate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YKM9 at UniProt or InterPro

Protein Sequence (203 amino acids)

>RR42_RS28090 carbon-phosphorus lyase (Cupriavidus basilensis FW507-4G11)
MPAGRHGALAPMLLPGFDDAVPSAQRTFRAALDAMSHPGSIGELAEPCGVPQGLSPGLSA
LLLALVDSDTPLWLPPETPEGVRAFLRFHCGCPLVAQVAQAAFVVVPAGHAVPDLMACAQ
GDPAYPDRSATLLIEVASLDSGPEVTLRGPGIETHATLAVQGLPADFWTQWQANHARFPL
GVDVLLTSGSALCALPRTTQAEA