Protein Info for RR42_RS27800 in Cupriavidus basilensis FW507-4G11

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 PF00005: ABC_tran" amino acids 23 to 166 (144 residues), 123.7 bits, see alignment E=9e-40 PF08402: TOBE_2" amino acids 283 to 349 (67 residues), 36.7 bits, see alignment E=3.8e-13

Best Hits

Swiss-Prot: 44% identical to POTA_PSEF5: Spermidine/putrescine import ATP-binding protein PotA (potA) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 85% identity to reh:H16_B1603)

Predicted SEED Role

"Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YJ34 at UniProt or InterPro

Protein Sequence (357 amino acids)

>RR42_RS27800 ABC transporter ATP-binding protein (Cupriavidus basilensis FW507-4G11)
MHEPTTITLRHCGKTFADGTLALQPLDLDIGAGETVVLLGPSGCGKTTTLRIIAGLEFPD
AGGVVMFGDNDVTPLPIEQRGVGMVFQSYALFPNMTVAENIAYGLRVRRIDAAARRRRVD
EMLAMMHLGPFAERRIDQLSGGQRQRVALARAIAVQPRVLLLDEPLTALDAKLRDALRAD
INQLLRSLHITAVYVTHDQAEAMALGDRIIVMDRGRIAQTGTPQQIYRAPANAFVADFIG
TMNRLPAVLEADAWRVPGGLVPRHGTAASLAAAPSPRAELLFRPEDVALAQAEDAHLGGS
VVTALFLGNYTRLLVDVGAPAPLVVDTTRRDGWLAGDRVGLRLDTGHLITLPEALAA