Protein Info for RR42_RS26465 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 transmembrane" amino acids 25 to 54 (30 residues), see Phobius details amino acids 62 to 84 (23 residues), see Phobius details amino acids 96 to 114 (19 residues), see Phobius details amino acids 120 to 148 (29 residues), see Phobius details amino acids 161 to 184 (24 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 251 to 275 (25 residues), see Phobius details amino acids 287 to 306 (20 residues), see Phobius details amino acids 318 to 337 (20 residues), see Phobius details amino acids 438 to 461 (24 residues), see Phobius details amino acids 473 to 495 (23 residues), see Phobius details amino acids 505 to 524 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 26 to 233 (208 residues), 98.9 bits, see alignment E=3.4e-32 amino acids 434 to 533 (100 residues), 24.7 bits, see alignment E=1.1e-09 PF07690: MFS_1" amino acids 48 to 332 (285 residues), 87.8 bits, see alignment E=7e-29

Best Hits

KEGG orthology group: None (inferred from 81% identity to reh:H16_B0809)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YB43 at UniProt or InterPro

Protein Sequence (534 amino acids)

>RR42_RS26465 MFS transporter (Cupriavidus basilensis FW507-4G11)
MTISLANDGAAVRKQGMTREERKVILASSFGALMEWYDFYIYAALAVYFGALFFPPGNET
TAFLASLATFGAGFLVRPVGALLFGRLGDKIGRKHTFLVTILLMGIATVGVGLLPTYGQI
GITATILLVVLRLLQGLALGGEVGGAVTYVAEHSPVEKRGLYTSSLQTTATLGLLSSLLV
VYLLKTLLTEAQFREWGWRLPFLVSFLMLVVSVYIRGKLHESPIFARMKAGNATSKSPIL
DSFTNWANLKYVLLLFVVASGLGAIFGTGHFYTMFFVNKTLHVPLELVHLLIGIALVIAT
PCYLFFGWLSDRIGRKHIMMAACLLAALTTQPIFRALTHYANPALEQFQQRNTVQLRAGD
CHFRLFAEPVSACDKVKGYLTDLGVGYEFTQIDAGAQPALRIGGTTLQGFDKAAIKQALV
AAGWTEHADPAAINRPMLFLMLLIPILLLAMVYGPLAAFMVELFPARIRYTSLSLPFHLG
AGWVGGMLSFVVTAMNVSSGNVYFGLWYPVSIAAIAFVVGMVFVPETRGRNLDT