Protein Info for RR42_RS26215 in Cupriavidus basilensis FW507-4G11

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 PF01590: GAF" amino acids 24 to 150 (127 residues), 37.4 bits, see alignment E=3.7e-13 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 157 to 323 (167 residues), 125.8 bits, see alignment E=6.9e-41 PF00990: GGDEF" amino acids 161 to 321 (161 residues), 120.3 bits, see alignment E=7.1e-39

Best Hits

KEGG orthology group: None (inferred from 62% identity to bpy:Bphyt_2139)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YL44 at UniProt or InterPro

Protein Sequence (325 amino acids)

>RR42_RS26215 diguanylate cyclase (Cupriavidus basilensis FW507-4G11)
MDASAQHAEPSVIDWLLHDDQVIRECFRHAAAILKNATGAAMTAVTLLDEEHQHYRAAVG
MPLSPISRKHSLCDHVARHGDLFVLEDALADPRFGECVLVRCFPFVRFYAAIPIKGPCGT
VVGALCAMDSAPHRITLAQCEVFRHLRAMVENDLKLRTATAIDPLTQLFNRRAMLESVRR
RWHETADGEEIGAVMVDVDWFKRYNDAYGHPAGDTCLREVASVLQSIADAHRMIAGRLGG
EEFGLLLCGAPRPALETALEDLRLSVERLKIEHRGSPFGSVTLSIGASLARKKGAVEPGS
REGVALADRALYMAKADGRNKVVII