Protein Info for RR42_RS25225 in Cupriavidus basilensis FW507-4G11

Annotation: NAD(P) transhydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 107 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 36 to 57 (22 residues), see Phobius details amino acids 64 to 85 (22 residues), see Phobius details PF12769: PNTB_4TM" amino acids 11 to 94 (84 residues), 120 bits, see alignment E=2.4e-39

Best Hits

KEGG orthology group: K00324, NAD(P) transhydrogenase subunit alpha [EC: 1.6.1.2] (inferred from 91% identity to rso:RSc2732)

Predicted SEED Role

"NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)" in subsystem Phosphate metabolism (EC 1.6.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.1.2

Use Curated BLAST to search for 1.6.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YKI6 at UniProt or InterPro

Protein Sequence (107 amino acids)

>RR42_RS25225 NAD(P) transhydrogenase (Cupriavidus basilensis FW507-4G11)
MEMTNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTEG
GVGRAMGTLAVALAAVNVFGGFLVTQRMLEMFKKKEPKAKAASKEGV