Protein Info for RR42_RS25065 in Cupriavidus basilensis FW507-4G11

Annotation: 2-methylcitrate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 PF03972: MmgE_PrpD_N" amino acids 22 to 256 (235 residues), 183.6 bits, see alignment E=3.9e-58 PF19305: MmgE_PrpD_C" amino acids 283 to 455 (173 residues), 84.1 bits, see alignment E=1.1e-27

Best Hits

KEGG orthology group: None (inferred from 77% identity to adn:Alide_2914)

Predicted SEED Role

"Immune-responsive protein 1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YHI9 at UniProt or InterPro

Protein Sequence (470 amino acids)

>RR42_RS25065 2-methylcitrate dehydratase (Cupriavidus basilensis FW507-4G11)
MTTTQSDSSSPPNCPPLEQAVVRLIQDLTFDQLDAPAHAGVSRLMRDQLALQVGTSQMPW
SHQVLAFAIAQQRPGRSRVAASTATMSAADAAFVNGAYGHGFEYDDAHGASASHPGSCVI
PAALAIGEELGSTLEEVITAIVAGYEVYTRIGVLAAPDLLKRGYHPHAVLSSFGAAAVSA
KLRRFDAETTLHALSIALSHAAGTTEYTSTGGSVKRVHAGIGTRSGMVSADMAQVGITGP
RAFLSGNKGFFRTLLQRGPGDRAEERFRLDQPFEIGTVWLKAYCACYCTHAYIDAIRPFA
ARRADIADIQARIHPAFNVVVGTANANAYEPKNIEHVQFSLPTQMAFAVLGMGNGYKVHR
DYLDGKLDMGPVKEVARGIGITEAPELEQRYPGKFVADVTVTFRDGSSEHVFVEDPIGSL
ANPMSEAEQDAKFMELTVDVLGEDRAQTLLATLRKMDPRLKTADLVALTH